Stevens–Johnson syndrome and toxic epidermal necrolysis: a review of diagnosis and management

R Frantz, S Huang, A Are, K Motaparthi - Medicina, 2021 - mdpi.com
Stevens–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare diseases
that are characterized by widespread epidermal necrosis and sloughing of skin. They are …

A Comprehensive Review of HLA and Severe Cutaneous Adverse Drug Reactions: Implication for Clinical Pharmacogenomics and Precision Medicine

C Kloypan, N Koomdee, P Satapornpong, T Tempark… - Pharmaceuticals, 2021 - mdpi.com
Human leukocyte antigen (HLA) encoded by the HLA gene is an important modulator for
immune responses and drug hypersensitivity reactions as well. Genetic polymorphisms of …

Drug-induced severe cutaneous adverse reactions: insights into clinical presentation, immunopathogenesis, diagnostic methods, treatment, and pharmacogenomics

T Tempark, S John, P Rerknimitr… - Frontiers in …, 2022 - frontiersin.org
SCARs are rare and life-threatening hypersensitivity reactions. In general, the increased
duration of hospital stays and the associated cost burden are common issues, and in the …

A review of the systemic treatment of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis

HC Chang, TJ Wang, MH Lin, TJ Chen - Biomedicines, 2022 - mdpi.com
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are uncommon but
life-threatening diseases mostly caused by drugs. Although various systemic …

Update on Stevens–Johnson syndrome and toxic epidermal necrolysis: diagnosis and management

H Shah, R Parisi, E Mukherjee, EJ Phillips… - American Journal of …, 2024 - Springer
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are the most
severe cutaneous adverse reactions that are typically drug-induced in adults. Both SJS and …

[HTML][HTML] NSAID (nonsteroidal anti-inflammatory drugs) Induced Stevens Johnson Syndrome in a 50-year-old woman: A case study

N Faraji, R Goli, P Mohsennezhad, Y Mohammadpour… - Toxicology Reports, 2024 - Elsevier
Abstract Stevens-Johnson Syndrome (SJS) is a severe and rare adverse drug reaction
associated with significant morbidity and mortality. Although SJS is commonly triggered by …

Ophthalmic Aspects of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Narrative Review

G Tóth, A Lukács, F Schirra, GL Sándor, P Killik… - Ophthalmology and …, 2023 - Springer
The aim of our review article was to summarize the current literature on Stevens–Johnson
syndrome (SJS) and its severe form, toxic epidermal necrolysis (TEN). SJS/TEN is a serious …

[HTML][HTML] A compilation of drug etiologies of stevens-johnson syndrome and toxic epidermal necrolysis

IT Abulatan, SG Ben-David, LA Morales-Colon… - Cureus, 2023 - ncbi.nlm.nih.gov
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are adverse
reactions that affect the mucocutaneous surfaces by causing necrosis and detachment of the …

Immune-related uncommon adverse events in patients with cancer treated with immunotherapy

V Albarrán-Artahona, JC Laguna, T Gorría… - Diagnostics, 2022 - mdpi.com
Immunotherapy has dramatically changed the therapeutic landscape of oncology, and has
become standard of care in multiple cancer types in front or late lines of therapy, with some …

Allopurinol: clinical considerations in the development and treatment of Stevens-Johnson syndrome, toxic epidermal necrolysis, and other associated drug reactions

KM Dillman, AM Hawkins, AR Ragland, GC Wester… - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Allopurinol lowers urate production through the inhibition of xanthine oxidase. It is
oxidatively hydroxylated to oxypurinol and is the most prescribed medication for gout …