Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …

Oxidative stress is a component of many diseases, including atherosclerosis, chronic
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …

Iron homeostasis disturbance has been implicated in Alzheimer's disease (AD), and excess
iron exacerbates oxidative damage and cognitive defects. Ferroptosis is a nonapoptotic form …

Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …

Treatments for Alzheimer's disease (AD) directed against the prominent amyloid plaque
neuropathology are yet to be proved effective despite many phase 3 clinical trials. There are …

Oxidative stress is known to play an important role in the pathogenesis of a number of
diseases. In particular, it is linked to the etiology of Alzheimer's disease (AD), an age-related …

Alzheimer's disease (AD) is an insidious and progressive neurodegenerative disorder that
affects millions of people worldwide. Although the pathogenesis remains obscure, there are …

Background Iron is essential for many types of biological processes. However, excessive
iron can be cytotoxic and can lead to many diseases. Since ferroptosis, which is an iron …

As the median age of the population increases, the number of individuals with Alzheimer's
disease (AD) and the associated socio-economic burden are predicted to worsen. While …