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Experimental tools and emerging principles of organellar mechanotransduction
K Li, YN Jan - Trends in Cell Biology, 2025 - cell.com
Mechanotransduction is the process by which cells detect mechanical forces and convert
them into biochemical or electrical signals. This process occurs across various cellular …
them into biochemical or electrical signals. This process occurs across various cellular …
Two-pore channel regulators-Who is in control?
R Deutsch, V Kudrina, M Freichel, C Grimm - Frontiers in Physiology, 2025 - frontiersin.org
Two-pore channels (TPCs) are adenine nucleotide and phosphoinositide regulated cation
channels. NAADP activates and ATP blocks TPCs, while the endolysosomal …
channels. NAADP activates and ATP blocks TPCs, while the endolysosomal …
Structural basis for growth factor and nutrient signal integration on the lysosomal membrane by mTORC1
Mechanistic target of rapamycin complex 1 (mTORC1), which consists of mTOR, Raptor, and
mLST8, receives signaling inputs from growth factor signals and nutrients. These signals are …
mLST8, receives signaling inputs from growth factor signals and nutrients. These signals are …