Poly (lactic acid)-based microparticles for drug delivery applications: An overview of recent advances

A Vlachopoulos, G Karlioti, E Balla, V Daniilidis… - Pharmaceutics, 2022 - mdpi.com
The sustained release of pharmaceutical substances remains the most convenient way of
drug delivery. Hence, a great variety of reports can be traced in the open literature …

[HTML][HTML] Growth factor delivery using extracellular matrix-mimicking substrates for musculoskeletal tissue engineering and repair

RCH Gresham, CS Bahney, JK Leach - Bioactive Materials, 2021 - Elsevier
Therapeutic approaches for musculoskeletal tissue regeneration commonly employ growth
factors (GFs) to influence neighboring cells and promote migration, proliferation, or …

Review of emerging nanotechnology in bone regeneration: progress, challenges, and perspectives

H Hajiali, L Ouyang, V Llopis-Hernandez, O Dobre… - Nanoscale, 2021 - pubs.rsc.org
The application of nanotechnology to regenerative medicine has increased over recent
decades. The development of materials that can influence biology at the nanoscale has …

Soybean lecithin‐mediated nanoporous plga microspheres with highly entrapped and controlled released BMP‐2 as a stem cell platform

D Wei, R Qiao, J Dao, J Su, C Jiang, X Wang, M Gao… - Small, 2018 - Wiley Online Library
Injectable polymer microsphere‐based stem cell delivery systems have a severe problem
that they do not offer a desirable environment for stem cell adhesion, proliferation, and …

Non-invasive production of multi-compartmental biodegradable polymer microneedles for controlled intradermal drug release of labile molecules

M Battisti, R Vecchione, C Casale… - … in Bioengineering and …, 2019 - frontiersin.org
Transdermal drug delivery represents an appealing alternative to conventional drug
administration systems. In fact, due to their high patient compliance, the development of …

Cell and protein compatible 3D bioprinting of mechanically strong constructs for bone repair

MJ Sawkins, P Mistry, BN Brown, KM Shakesheff… - …, 2015 - iopscience.iop.org
Rapid prototy** of bone tissue engineering constructs often utilizes elevated
temperatures, organic solvents and/or UV light for materials processing. These harsh …

Stem cells for cutaneous wound healing

GTS Kirby, SJ Mills, AJ Cowin… - BioMed research …, 2015 - Wiley Online Library
Optimum healing of a cutaneous wound involves a well‐orchestrated cascade of biological
and molecular processes involving cell migration, proliferation, extracellular matrix …

[HTML][HTML] Injectable and porous PLGA microspheres that form highly porous scaffolds at body temperature

O Qutachi, JR Vetsch, D Gill, H Cox, DJ Scurr… - Acta biomaterialia, 2014 - Elsevier
Injectable scaffolds are of interest in the field of regenerative medicine because of their
minimally invasive mode of delivery. For tissue repair applications, it is essential that such …

Remotely activated mechanotransduction via magnetic nanoparticles promotes mineralization synergistically with bone morphogenetic protein 2: applications for …

JR Henstock, M Rotherham, H Rashidi… - Stem cells …, 2014 - academic.oup.com
Bone requires dynamic mechanical stimulation to form and maintain functional tissue, yet
mechanical stimuli are often lacking in many therapeutic approaches for bone regeneration …

Controlled release of BMP‐2 from a sintered polymer scaffold enhances bone repair in a mouse calvarial defect model

CV Rahman, D Ben‐David, A Dhillon… - Journal of tissue …, 2014 - Wiley Online Library
Sustained and controlled delivery of growth factors, such as bone morphogenetic protein 2
(BMP‐2), from polymer scaffolds has excellent potential for enhancing bone regeneration …