Since the development of antibody-production techniques, a number of immunoglobulins
have been developed on a large scale using conventional methods. Hybridoma technology …

G protein-coupled receptors are of key significance for biomedical research. Streamlined
approaches for their efficient recombinant production are of pivotal interest in order to …

The mitochondria are highly dynamic organelles, carefully maintaining network homeostasis
by regulating mitochondrial fusion and fission. Mitochondrial dynamics are involved in the …

Protein glycosylation is an essential posttranslational modification that affects a myriad of
physiologic processes. Humans with genetic defects in glycosylation, which result in …

Significant attention has been shifted toward the use and development of biodegradable
polymeric materials to mitigate environmental accumulation and potential health impacts …

Background Heart failure (HF) presents a massive burden to health care with a complex
pathophysiology that results in HF with reduced left ventricle ejection fraction (EF) or HF with …

Undergraduate laboratory courses are essential to teaching core principles in STEM. This
course, Quantitative Biological Methods, provides a unique approach to teaching molecular …

Mass-spectrometry (MS) based phosphoproteomics is increasingly used to explore aberrant
cellular signaling and kinase driver activity, aiming to improve kinase inhibitor (KI) treatment …

The concepts of protein purification are often taught in undergraduate biology and
biochemistry lectures and reinforced during laboratory exercises; however, very few …

The purpose of this thesis was to assist the ongoing development and enhancement of
undergraduate biochemical literacy in the UK using pragmatic mixed-methods. Seven areas …