Allergic diseases, such as respiratory, cutaneous, and food allergy, have dramatically
increased in prevalence over the last few decades. Recent research points to a central role …

Although human colonization by facultative bacterial pathogens, such as Staphylococcus
aureus, represents a major risk factor for invasive infections, the commensal lifestyle of such …

The airway microbiome has an important role in asthma pathophysiology. However, little is
known on the relationships between the airway microbiome of asthmatic children, loss of …

The prevalence of allergic diseases is regarded as one of the key challenges in health
worldwide. Although the precise mechanisms underlying this rapid increase in prevalence …

Background Studies indicate that the nasal microbiome may correlate strongly with the
presence or future risk of childhood asthma. Objectives In this study, we tested whether …

The importance of the microbiome, and of the gut-lung axis in the origin and persistence of
asthma, is an ongoing field of investigation. The process of microbial colonisation in the first …

Different effector arms of the immune system are optimized to protect from different classes
of pathogens. In some cases, pathogens manipulate the host immune system to promote the …

Staphylococcus aureus (S. aureus) is a dangerous pathogen and a leading cause of both
nosocomial and community acquired bacterial infection worldwide. However, on the other …

The prevalence of many chronic noncommunicable diseases has been steadily rising over
the past six decades. During this time, over 350,000 new chemical substances have been …

Asthma is a heterogenous chronic inflammatory lung disease with endotypes that manifest
different immune system profiles, severity, and responses to current therapies. Regardless of …