Nephrotic syndrome

C Wang, LA Greenbaum - Pediatric Clinics, 2019 - pediatric.theclinics.com
There are 4 classic features of nephrotic syndrome (Box 1). 1 There are many different
causes of nephrotic syndrome (Table 1), but they share a common pathophysiology …

Treatment of C3 glomerulopathy in adult kidney transplant recipients: a systematic review

ML Gonzalez Suarez, C Thongprayoon, P Hansrivijit… - Medical …, 2020 - mdpi.com
Background: C3 glomerulopathy (C3G), a rare glomerular disease mediated by alternative
complement pathway dysregulation, is associated with a high rate of recurrence and graft …

[HTML][HTML] C3 glomerulonephritis and dense deposit disease share a similar disease course in a large United States cohort of patients with C3 glomerulopathy

AS Bomback, D Santoriello, RS Avasare… - Kidney international, 2018 - Elsevier
C3 glomerulonephritis (C3GN) and dense deposit disease comprise the two classes of C3
glomerulopathy. Studies from Europe and Asia have aided our understanding of this …

Kidney transplantation in C3 glomerulopathy: a case series

R Regunathan-Shenk, RS Avasare, W Ahn… - American Journal of …, 2019 - Elsevier
Rationale & Objective C3 glomerulopathy (C3G), a form of glomerulonephritis associated
with dysregulation of the alternative complement pathway, occurs either as dense deposit …

Demographic, clinical characteristics and treatment outcomes of immune-complex membranoproliferative glomerulonephritis and C3 glomerulonephritis in Japan: A …

N Nakagawa, M Mizuno, S Kato, S Maruyama, H Sato… - PLoS …, 2021 - journals.plos.org
The reclassification of membranoproliferative glomerulonephritis (MPGN) into immune-
complex MPGN (IC-MPGN) and C3 glomerulopathy (C3G) based on immunofluorescence …

C3 glomerulopathy and eculizumab: a report on four paediatric cases

C Lebreton, J Bacchetta, F Dijoud, L Bessenay… - Pediatric …, 2017 - Springer
Background Eculizumab may be used to treat C3-glomerulopathy (C3G), a rare but severe
glomerular disease. Diagnosis and Treatment Patients 1, 2 and 3 were diagnosed with …

Therapy and outcomes of C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis

P Khandelwal, S Bhardwaj, G Singh, A Sinha… - Pediatric …, 2021 - Springer
Background Data on therapy and outcome of dense deposit disease (DDD), C3
glomerulonephritis (C3GN), and immune-complex MPGN (IC-MPGN) in children are limited …

Outcome of membranoproliferative glomerulonephritis and C3-glomerulopathy in children and adolescents

J Holle, L Berenberg-Goßler, K Wu, O Beringer… - Pediatric …, 2018 - Springer
Background Membranoproliferative glomerulonephritis (MPGN) is a rare cause of
glomerulopathy in children. Recently, a new classification based on immunohistological …

Long-term follow-up including extensive complement analysis of a pediatric C3 glomerulopathy cohort

MAHM Michels, KL Wijnsma, RAJ Kurvers, D Westra… - Pediatric …, 2022 - Springer
Abstract Background C3 glomerulopathy (C3G) is a rare kidney disorder characterized by
predominant glomerular depositions of complement C3. C3G can be subdivided into dense …

[HTML][HTML] Long-term outcomes of C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis in children

A Kirpalani, N Jawa, WE Smoyer, C Licht… - Kidney International …, 2020 - Elsevier
Introduction The reclassification of membranoproliferative glomerulonephritis (MPGN) into
immune-complex MPGN (IC-MPGN) and C3 glomerulopathy (C3G) has provided insights …