Particle engineering for pulmonary drug delivery

AHL Chow, HHY Tong, P Chattopadhyay… - Pharmaceutical …, 2007 - Springer
With the rapidly growing popularity and sophistication of inhalation therapy, there is an
increasing demand for tailor-made inhalable drug particles capable of affording the most …

Interactive apparatus and method for real-time profiling of inhalation efforts

D Overfield, CR Sahi, B Adamo, PS Kinsey… - US Patent …, 2016 - Google Patents
D189, 076 3,337,740 3,407.203 3,518,340 3,622,053 3,669,113 3,823,816 3,823,843
3,856,142 3,906,950 3,921,637 3,976,773 3,980,074 3,998,226 4,013,075 4,018,619 …

RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering …

J McSwiggen, L Beigelman, P Pavco - US Patent 7,176,304, 2007 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …

Engineered particles and methods of use

TE Tarara, JG Weers, A Kabalnov, EG Schutt… - US Patent …, 2007 - Google Patents
Engineered particles are provided may be used for the delivery of a bioactive agent to the
respiratory tract of a patient. The particles may be used in the form of dry poWders or in the …

RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA)

P Haeberli, L Beigelman - US Patent App. 11/098,303, 2005 - Google Patents
US20050282188A1 - RNA interference mediated inhibition of gene expression using short
interfering nucleic acid (siNA) - Google Patents US20050282188A1 - RNA interference …

Substituted diketopiperazine analogs for use as drug delivery agents

KS Kraft - US Patent 8,314,106, 2012 - Google Patents
6,663,898 B2 12/2003 Milstein closed a substituted analogs of 3, 6-di (alkyl-4 aminobutyl)-
6,838,076 B2 1/2005 Patton et al. 2, 5-diketopiperazine (which may also be referred to …

RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)

J McSwiggen, H Robin - US Patent App. 10/840,731, 2005 - Google Patents
US20050137153A1 - RNA interference mediated inhibition of alpha-1 antitrypsin (AAT)
gene expression using short interfering nucleic acid (siNA) - Google Patents …

RNA interference mediated inhibition of TNF and TNF receptor gene expression using short interfering nucleic acid (siNA)

J McSwiggen, L Beigelman - US Patent App. 10/923,470, 2005 - Google Patents
This invention relates to compounds, compositions, and methods useful for modulating
tumor necrosis factor and/or tumor necrosis factor receptor gene expression using short …

In-situ gel formation of pectin

Y Ni, KM Yates - US Patent 6,777,000, 2004 - Google Patents
In-situ gelation of a pectic substance. Composition, method of preparation, and method of
use of a pectin in-situ gelling formulation for the delivery and sustained release of a …

RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)

M Cancilla, JJ Cunningham, MW Flanagan… - US Patent …, 2016 - Google Patents
2013-04-25 Assigned to MERCK SHARP & DOHME CORP. reassignment MERCK SHARP
& DOHME CORP. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …