In the last few decades, several natural bioactive agents have been widely utilized in the
treatment and prevention of many diseases owing to their unique and versatile therapeutic …

Biomacromolecular therapeutic agents, particularly proteins, antigens, enzymes, and nucleic
acids are emerging as powerful candidates for the treatment of various diseases and the …

The oral drug administration was convenient and comfortable route for patients.
Nevertheless, the oral uptake efficiency of many therapeutic agents was limited by …

Non-parenteral drug delivery routes primarily remove the local pain at the injection site. The
drugs administered through the oral route encounter the process of hepatic first pass …

Proteins and peptides are widely indicated in many diseased states. Parenteral route is the
most commonly em-ployed method of administration for therapeutic proteins and peptides …

Chitosan nanoparticles (CSNPs) are the nanostructures of chitosan biopolymer which is
derived from chitin polysaccharide, the main component of crustacean shells. Chitosan is a …

The physicochemical properties of nanobiomaterials, such as their small size and high
surface area ratio, make them attractive, novel drug-carriers, with increased cellular …

To develop more effective anticancer mucoadhesive drug delivery system for the treatment
of colorectal cancer, chitosan based nanogels (NGs) were prepared by electrostatic …

This study aimed to investigate the efficacy of nanoparticles based on chitosan as a vehicle
for oral antigen delivery in fish vaccination. Carboxymethyl chitosan/chitosan nanoparticles …

The influence of nanoparticle (NP) formulations on the pharmacokinetic, pharmacodynamic
and biodistribution profiles of peptide-and protein-like drugs following oral administration is …