Immunotherapies for hepatocellular carcinoma
Liver cancer, more specifically hepatocellular carcinoma (HCC), is the second leading
cause of cancer-related death and its incidence is increasing globally. Around 50% of …
cause of cancer-related death and its incidence is increasing globally. Around 50% of …
The liver cancer immune microenvironment: Therapeutic implications for hepatocellular carcinoma
The liver is the sixth most common site of primary cancer in humans and the fourth leading
cause of cancer‐related death in the world. Hepatocellular carcinoma (HCC) accounts for …
cause of cancer‐related death in the world. Hepatocellular carcinoma (HCC) accounts for …
The immunology of hepatocellular carcinoma
M Ringelhan, D Pfister, T O'Connor, E Pikarsky… - Nature …, 2018 - nature.com
In contrast to most other malignancies, hepatocellular carcinoma (HCC), which accounts for
approximately 90% of primary liver cancers, arises almost exclusively in the setting of …
approximately 90% of primary liver cancers, arises almost exclusively in the setting of …
Therapeutic strategies for hepatitis B virus infection: towards a cure
Chronic hepatitis B virus (HBV) infection is a common cause of liver disease globally, with a
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …
Liver immunology and its role in inflammation and homeostasis
The human liver is usually perceived as a non-immunological organ engaged primarily in
metabolic, nutrient storage and detoxification activities. However, we now know that the …
metabolic, nutrient storage and detoxification activities. However, we now know that the …
Immunology in the liver—from homeostasis to disease
The liver is a central immunological organ with a high exposure to circulating antigens and
endotoxins from the gut microbiota, particularly enriched for innate immune cells …
endotoxins from the gut microbiota, particularly enriched for innate immune cells …
Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy
L Yang, Z Chu, M Liu, Q Zou, J Li, Q Liu… - Journal of hematology & …, 2023 - Springer
Amino acids are basic nutrients for immune cells during organ development, tissue
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …
A global scientific strategy to cure hepatitis B
Chronic hepatitis B virus (HBV) infection is a global public health challenge on the same
scale as tuberculosis, HIV, and malaria. The International Coalition to Eliminate HBV (ICE …
scale as tuberculosis, HIV, and malaria. The International Coalition to Eliminate HBV (ICE …
A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook
A Kramvis, KM Chang, M Dandri, P Farci… - Nature Reviews …, 2022 - nature.com
Globally, 296 million people are infected with hepatitis B virus (HBV), and approximately one
million people die annually from HBV-related causes, including liver cancer. Although there …
million people die annually from HBV-related causes, including liver cancer. Although there …
Friend or foe? The elusive role of hepatic stellate cells in liver cancer
Liver fibrosis is a substantial risk factor for the development and progression of liver cancer,
which includes hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma …
which includes hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma …