Oligosaccharide analysis by mass spectrometry: a review of recent developments

MJ Kailemia, LR Ruhaak, CB Lebrilla… - Analytical …, 2014 - ACS Publications
Carbohydrates are central players in a number of important biological processes including
cell signaling, cell adhesion, and the regulation of biochemical pathways. Unlike nucleic …

Chemical glycoproteomics

KK Palaniappan, CR Bertozzi - Chemical reviews, 2016 - ACS Publications
Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …

Glycomic and glycoproteomic analysis of glycoproteins—a tutorial

A Shajahan, C Heiss, M Ishihara, P Azadi - Analytical and bioanalytical …, 2017 - Springer
The structural analysis of glycoproteins is a challenging endeavor and is under steadily
increasing demand, but only a very limited number of labs have the expertise required to …

Recent advances in analytical approaches for glycan and glycopeptide quantitation

DG Delafield, L Li - Molecular & Cellular Proteomics, 2021 - ASBMB
Growing implications of glycosylation in physiological occurrences and human disease have
prompted intensive focus on revealing glycomic perturbations through absolute and relative …

Recent advances in hydrophilic interaction liquid chromatography (HILIC) for structural glycomics

G Zauner, AM Deelder, M Wuhrer - Electrophoresis, 2011 - Wiley Online Library
This review presents recent progress in employing hydrophilic interaction liquid
chromatography (HILIC) for glycan and glycopeptides analysis. After an introduction of this …

Metabolism mechanism of glycosaminoglycans by the gut microbiota: Bacteroides and lactic acid bacteria: A review

J Dong, Y Cui, X Qu - Carbohydrate Polymers, 2024 - Elsevier
Glycosaminoglycans (GAGs), as a class of biopolymers, play pivotal roles in various
biological metabolisms such as cell signaling, tissue development, cell apoptosis, immune …

Developments in mass spectrometry for glycosaminoglycan analysis: a review

LE Pepi, P Sanderson, M Stickney, IJ Amster - Molecular & Cellular …, 2021 - ASBMB
This review covers recent developments in glycosaminoglycan (GAG) analysis via mass
spectrometry (MS). GAGs participate in a variety of biological functions, including cellular …

GlycReSoft: a software package for automated recognition of glycans from LC/MS data

E Maxwell, Y Tan, Y Tan, H Hu, G Benson, K Aizikov… - 2012 - journals.plos.org
Glycosylation modifies the physicochemical properties and protein binding functions of
glycoconjugates. These modifications are biosynthesized in the endoplasmic reticulum and …

State‐of‐the‐art glycosaminoglycan characterization

A Zappe, RL Miller, WB Struwe… - Mass Spectrometry …, 2022 - Wiley Online Library
Glycosaminoglycans (GAGs) are heterogeneous acidic polysaccharides involved in a range
of biological functions. They have a significant influence on the regulation of cellular …

Quantification of neutral human milk oligosaccharides by graphitic carbon high-performance liquid chromatography with tandem mass spectrometry

Y Bao, C Chen, DS Newburg - Analytical Biochemistry, 2013 - Elsevier
Defining the biological roles of human milk oligosaccharides (HMOS) requires an efficient,
simple, reliable, and robust analytical method for simultaneous quantification of …