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Bioactive compounds from marine actinomycetes
Actinomycetes are one of the most efficient groups of secondary metabolite producers and
are very important from an industrial point of view. Among its various genera, Streptomyces …
are very important from an industrial point of view. Among its various genera, Streptomyces …
Simple glycolipids of microbes: chemistry, biological activity and metabolic engineering
Glycosylated lipids (GLs) are added-value lipid derivatives of great potential. Besides their
interesting surface activities that qualify many of them to act as excellent ecological …
interesting surface activities that qualify many of them to act as excellent ecological …
Surfactants tailored by the class Actinobacteria
Globally the change towards the establishment of a bio-based economy has resulted in an
increased need for bio-based applications. This, in turn, has served as a driving force for the …
increased need for bio-based applications. This, in turn, has served as a driving force for the …
Emerging paradigms of viral diseases and paramount role of natural resources as antiviral agents
In the current scenario, the increasing prevalence of diverse microbial infections as well as
emergence and re-emergence of viral epidemics with high morbidity and mortality rates are …
emergence and re-emergence of viral epidemics with high morbidity and mortality rates are …
Structure Assignment, Total Synthesis, and Antiviral Evaluation of Cycloviracin B1
A Fürstner, M Albert, J Mlynarski… - Journal of the …, 2003 - ACS Publications
The first total synthesis of the antivirally active glycolipid cycloviracin B1 (1) is described. The
approach is based on a two-directional synthesis strategy which constructs the C 2 …
approach is based on a two-directional synthesis strategy which constructs the C 2 …
[HTML][HTML] A novel alkaliphilic Streptomyces inhibits ESKAPE pathogens
In an effort to stem the rising tide of multi-resistant bacteria, researchers have turned to niche
environments in the hope of discovering new varieties of antibiotics. We investigated an …
environments in the hope of discovering new varieties of antibiotics. We investigated an …
Unleashing the Potential of Microbial Natural Products in Drug Discovery: Focusing on Streptomyces as Antimicrobials Goldmine
The natural product specialized metabolites produced by microbes and plants are the
backbone of our current drugs. Ironically, we are in a golden age of understanding natural …
backbone of our current drugs. Ironically, we are in a golden age of understanding natural …
Cyclic natural product oligomers: diversity and (bio) synthesis of macrocycles
Cyclic compounds are generally preferred over linear compounds for functional studies due
to their enhanced bioavailability, stability towards metabolic degradation, and selective …
to their enhanced bioavailability, stability towards metabolic degradation, and selective …
From antibiotic to antiviral: computational screening reveals a multi-targeting antibiotic from Streptomyces spp. against Nipah virus fusion proteins
Nipah Virus is a re-emerging zoonotic paramyxovirus that poses a significant threat to both
swine industry and human health. The pursuit of potential antiviral agents with both …
swine industry and human health. The pursuit of potential antiviral agents with both …
Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza Part II: Future compounds against …
In the first part of this overview, we described the life cycle of the influenza virus and the
pharmacological action of the currently available drugs. This second part provides an …
pharmacological action of the currently available drugs. This second part provides an …