Modification of lipid-based nanoparticles: An efficient delivery system for nucleic acid-based immunotherapy

C Zhang, Y Ma, J Zhang, JCT Kuo, Z Zhang, H **e… - Molecules, 2022 - mdpi.com
Lipid-based nanoparticles (LBNPs) are biocompatible and biodegradable vesicles that are
considered to be one of the most efficient drug delivery platforms. Due to the prominent …

[HTML][HTML] Decoding the role of S100 proteins in mammary gland regulation and their role in breast cancer metastasis

P Singh, SA Ali - Advances in Cancer Biology-Metastasis, 2023 - Elsevier
S100 proteins have emerged as key regulators in the mammary gland and have been
implicated in breast cancer development and metastasis. This review provides a …

Bioactive Oligopeptides from Ginseng (Panax ginseng Meyer) Suppress Oxidative Stress-Induced Senescence in Fibroblasts via NAD+/SIRT1/PGC-1α Signaling …

N Zhu, MH Xu, Y Li - Nutrients, 2022 - mdpi.com
The physicochemical properties and multiple bioactive effects of ginseng oligopeptides
(GOPs), plant-derived small molecule bioactive peptides, suggest a positive influence on …

Aryl hydrocarbon receptor activation ameliorates acute respiratory distress syndrome through regulation of Th17 and Th22 cells in the lungs

BL Holloman, A Cannon, K Wilson, P Nagarkatti… - MBio, 2023 - Am Soc Microbiol
Acute respiratory distress syndrome (ARDS) is triggered by a variety of insults, including
bacterial and viral infections, and this leads to high mortality. While the role of the aryl …

On the mechanism of miR-29b enhancement of etoposide toxicity in vitro

Z Dostál, J Buchtíková, J Mandrla, M Modrianský - Scientific Reports, 2024 - nature.com
MicroRNA hsa-miR-29 was connected to a number of malignancies. Its target genes are
many, among them Mcl-1 that is expressed in three possible isoforms, one of which is anti …

Trimetazidine alleviates bleomycin-induced pulmonary fibrosis by targeting the long noncoding RNA CBR3-AS1-mediated miRNA-29 and Resistin-Like Molecule …

AR Alzahrani, DI Mohamed… - Drug Design …, 2024 - Taylor & Francis
Introduction Pulmonary fibrosis (PF) and tissue remodeling can greatly impair pulmonary
function and often lead to fatal outcomes. Methodology In the present study, we explored a …

MicroRNAs influence and longevity

SA Eshkoor, N Ghodsian, M Akhtari-Zavare - Egyptian Journal of Medical …, 2022 - Springer
Background MiRNAs play critical roles in the regulation of cellular function, life span, and the
aging process. They can affect longevity positively and negatively through different aging …

[HTML][HTML] Noncoding RNAs as additional mediators of epigenetic regulation in nonalcoholic fatty liver disease

M Zaiou - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common cause of
chronic liver disorder worldwide. It represents a spectrum that includes a continuum of …

A brief review on the biology and effects of cellular and circulating micrornas on cardiac remodeling after infarction

M Parikh, GN Pierce - International Journal of Molecular Sciences, 2021 - mdpi.com
Despite advances in diagnostic, prognostic, and treatment modalities, myocardial infarction
(MI) remains a leading cause of morbidity and mortality. Impaired cellular signaling after an …

[HTML][HTML] MicroRNA-29b regulates pyroptosis involving calcific aortic valve disease through the STAT3/SOCS1 pathway

M Fang, B Li, X Li, Y Wang, Y Zhuang - International Journal of Cardiology, 2023 - Elsevier
Background CAVD (calcific aortic valve disease) involves an inflammatory response similar
to pyroptosis; therefore, we speculated that the progression of pyroptosis might be involved …