Modification of lipid-based nanoparticles: An efficient delivery system for nucleic acid-based immunotherapy
Lipid-based nanoparticles (LBNPs) are biocompatible and biodegradable vesicles that are
considered to be one of the most efficient drug delivery platforms. Due to the prominent …
considered to be one of the most efficient drug delivery platforms. Due to the prominent …
[HTML][HTML] Decoding the role of S100 proteins in mammary gland regulation and their role in breast cancer metastasis
S100 proteins have emerged as key regulators in the mammary gland and have been
implicated in breast cancer development and metastasis. This review provides a …
implicated in breast cancer development and metastasis. This review provides a …
Bioactive Oligopeptides from Ginseng (Panax ginseng Meyer) Suppress Oxidative Stress-Induced Senescence in Fibroblasts via NAD+/SIRT1/PGC-1α Signaling …
N Zhu, MH Xu, Y Li - Nutrients, 2022 - mdpi.com
The physicochemical properties and multiple bioactive effects of ginseng oligopeptides
(GOPs), plant-derived small molecule bioactive peptides, suggest a positive influence on …
(GOPs), plant-derived small molecule bioactive peptides, suggest a positive influence on …
Aryl hydrocarbon receptor activation ameliorates acute respiratory distress syndrome through regulation of Th17 and Th22 cells in the lungs
Acute respiratory distress syndrome (ARDS) is triggered by a variety of insults, including
bacterial and viral infections, and this leads to high mortality. While the role of the aryl …
bacterial and viral infections, and this leads to high mortality. While the role of the aryl …
On the mechanism of miR-29b enhancement of etoposide toxicity in vitro
Z Dostál, J Buchtíková, J Mandrla, M Modrianský - Scientific Reports, 2024 - nature.com
MicroRNA hsa-miR-29 was connected to a number of malignancies. Its target genes are
many, among them Mcl-1 that is expressed in three possible isoforms, one of which is anti …
many, among them Mcl-1 that is expressed in three possible isoforms, one of which is anti …
Trimetazidine alleviates bleomycin-induced pulmonary fibrosis by targeting the long noncoding RNA CBR3-AS1-mediated miRNA-29 and Resistin-Like Molecule …
AR Alzahrani, DI Mohamed… - Drug Design …, 2024 - Taylor & Francis
Introduction Pulmonary fibrosis (PF) and tissue remodeling can greatly impair pulmonary
function and often lead to fatal outcomes. Methodology In the present study, we explored a …
function and often lead to fatal outcomes. Methodology In the present study, we explored a …
MicroRNAs influence and longevity
SA Eshkoor, N Ghodsian, M Akhtari-Zavare - Egyptian Journal of Medical …, 2022 - Springer
Background MiRNAs play critical roles in the regulation of cellular function, life span, and the
aging process. They can affect longevity positively and negatively through different aging …
aging process. They can affect longevity positively and negatively through different aging …
[HTML][HTML] Noncoding RNAs as additional mediators of epigenetic regulation in nonalcoholic fatty liver disease
M Zaiou - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common cause of
chronic liver disorder worldwide. It represents a spectrum that includes a continuum of …
chronic liver disorder worldwide. It represents a spectrum that includes a continuum of …
A brief review on the biology and effects of cellular and circulating micrornas on cardiac remodeling after infarction
M Parikh, GN Pierce - International Journal of Molecular Sciences, 2021 - mdpi.com
Despite advances in diagnostic, prognostic, and treatment modalities, myocardial infarction
(MI) remains a leading cause of morbidity and mortality. Impaired cellular signaling after an …
(MI) remains a leading cause of morbidity and mortality. Impaired cellular signaling after an …
[HTML][HTML] MicroRNA-29b regulates pyroptosis involving calcific aortic valve disease through the STAT3/SOCS1 pathway
M Fang, B Li, X Li, Y Wang, Y Zhuang - International Journal of Cardiology, 2023 - Elsevier
Background CAVD (calcific aortic valve disease) involves an inflammatory response similar
to pyroptosis; therefore, we speculated that the progression of pyroptosis might be involved …
to pyroptosis; therefore, we speculated that the progression of pyroptosis might be involved …