Low grade gliomas are the most frequent brain tumors in children and encompass a
spectrum of histologic entities which are currently assigned World Health Organisation …

The mainstay of treatment for adult patients with gliomas, glioneuronal and neuronal tumors
consists of combinations of surgery, radiotherapy, and chemotherapy. For many systemic …

Background Detection of the BRAF V600E mutation in pediatric low-grade glioma has been
associated with a lower response to standard chemotherapy. In previous trials, dabrafenib …

PURPOSE BRAF V600 mutations occur in many childhood cancers, including approximately
20% of low-grade gliomas (LGGs). Here, we describe a phase I/II study establishing …

Pediatric low-grade gliomas (pLGG) are frequently driven by genetic alterations in the RAS-
mitogen-activated protein kinase (RAS/MAPK) pathway yet show unexplained variability in …

Background Paediatric low-grade glioma is the most common CNS tumour of childhood.
Although overall survival is good, disease often recurs. No single universally accepted …

Infant gliomas have paradoxical clinical behavior compared to those in children and adults:
low-grade tumors have a higher mortality rate, while high-grade tumors have a better …

The world of molecular profiling has undergone revolutionary changes over the last few
years as knowledge, technology, and even standard clinical practice have evolved. Broad …

Purpose BRAF V600 mutations are frequently found in several glioma subtypes, including
pleomorphic xanthoastrocytoma (PXA) and ganglioglioma and much less commonly in …

This article is a comprehensive review of the basic background, technique, and clinical
applications of artificial intelligence (AI) and radiomics in the field of neuro-oncology. A …