PIWI-interacting RNA: its biogenesis and functions
PIWI-interacting RNAs (piRNAs) are a class of small RNAs that are 24–31 nucleotides in
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
[HTML][HTML] Small RNAs as guardians of the genome
Transposons populate the landscape of all eukaryotic genomes. Often considered purely
genomic parasites, transposons can also benefit their hosts, playing roles in gene regulation …
genomic parasites, transposons can also benefit their hosts, playing roles in gene regulation …
LTR_retriever: a highly accurate and sensitive program for identification of long terminal repeat retrotransposons
Long terminal repeat retrotransposons (LTR-RTs) are prevalent in plant genomes. The
identification of LTR-RTs is critical for achieving high-quality gene annotation. Based on the …
identification of LTR-RTs is critical for achieving high-quality gene annotation. Based on the …
[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny
Comparative analysis of multiple genomes in a phylogenetic framework dramatically
improves the precision and sensitivity of evolutionary inference, producing more robust …
improves the precision and sensitivity of evolutionary inference, producing more robust …
Considering Transposable Element Diversification in De Novo Annotation Approaches
Transposable elements (TEs) are mobile, repetitive DNA sequences that are almost
ubiquitous in prokaryotic and eukaryotic genomes. They have a large impact on genome …
ubiquitous in prokaryotic and eukaryotic genomes. They have a large impact on genome …
Fine-grained annotation and classification of de novo predicted LTR retrotransposons
S Steinbiss, U Willhoeft, G Gremme… - Nucleic acids …, 2009 - academic.oup.com
Long terminal repeat (LTR) retrotransposons and endogenous retroviruses (ERVs) are
transposable elements in eukaryotic genomes well suited for computational identification …
transposable elements in eukaryotic genomes well suited for computational identification …
[HTML][HTML] UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery
Summary piRNAs silence transposons during germline development. In Drosophila,
transcripts from heterochromatic clusters are processed into primary piRNAs in the …
transcripts from heterochromatic clusters are processed into primary piRNAs in the …
An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila
D Olivieri, MM Sykora, R Sachidanandam… - The EMBO …, 2010 - embopress.org
In Drosophila, PIWI proteins and bound PIWI‐interacting RNAs (piRNAs) form the core of a
small RNA‐mediated defense system against selfish genetic elements. Within germline …
small RNA‐mediated defense system against selfish genetic elements. Within germline …
The piRNA pathway: a fly's perspective on the guardian of the genome
KA Senti, J Brennecke - Trends in Genetics, 2010 - cell.com
Throughout the eukaryotic lineage, small RNA silencing pathways protect the genome
against the deleterious influence of selfish genetic elements such as transposons. In …
against the deleterious influence of selfish genetic elements such as transposons. In …
Transposable elements and the evolution of insects
Insects are major contributors to our understanding of the interaction between transposable
elements (TEs) and their hosts, owing to seminal discoveries, as well as to the growing …
elements (TEs) and their hosts, owing to seminal discoveries, as well as to the growing …