[HTML][HTML] Pharmaceutical wastewater as Emerging Contaminants (EC): Treatment technologies, impact on environment and human health

K Samal, S Mahapatra, MH Ali - Energy Nexus, 2022 - Elsevier
A wide range of unregulated chemicals of synthetic origin or derived from natural sources,
which may be a contender for future regulations are called Emerging Contaminants (ECs) …

Use of zebrafish in drug discovery toxicology

S Cassar, I Adatto, JL Freeman, JT Gamse… - Chemical research in …, 2019 - ACS Publications
Unpredicted human safety events in clinical trials for new drugs are costly in terms of human
health and money. The drug discovery industry attempts to minimize those events with …

Zebrafish in toxicology and environmental health

K Bambino, J Chu - Current topics in developmental biology, 2017 - Elsevier
As manufacturing processes and development of new synthetic compounds increase to
keep pace with the expanding global demand, environmental health, and the effects of …

Anticancer drugs in wastewater and natural environments: A review on their occurrence, environmental persistence, treatment, and ecological risks

A Castellano-Hinojosa, MJ Gallardo-Altamirano… - Journal of Hazardous …, 2023 - Elsevier
The consumption of anticancer drugs (also known as chemotherapy drugs or antineoplastic
drugs) has augmented over the last decades due to increased cancer incidence. Although …

Zebrafish: an important tool for liver disease research

W Goessling, KC Sadler - Gastroenterology, 2015 - Elsevier
As the incidence of hepatobiliary diseases increases, we must improve our understanding of
the molecular, cellular, and physiological factors that contribute to the pathogenesis of liver …

Advancements in zebrafish applications for 21st century toxicology

GR Garcia, PD Noyes, RL Tanguay - Pharmacology & therapeutics, 2016 - Elsevier
The zebrafish model is the only available high-throughput vertebrate assessment system,
and it is uniquely suited for studies of in vivo cell biology. A sequenced and annotated …

DMSO concentrations up to 1% are safe to be used in the zebrafish embryo developmental toxicity assay

J Hoyberghs, C Bars, M Ayuso, C Van Ginneken… - Frontiers in …, 2021 - frontiersin.org
Dimethyl sulfoxide (DMSO) is a popular solvent for developmental toxicity testing of
chemicals and pharmaceuticals in zebrafish embryos. In general, it is recommended to keep …

[HTML][HTML] Anticancer drugs in the aquatic ecosystem: Environmental occurrence, ecotoxicological effect and risk assessment

D Li, H Chen, H Liu, D Schlenk, J Mu, S Lacorte… - Environment …, 2021 - Elsevier
Anticancer drugs are a group of therapeutic agents used to enhance cell death in targeted
cell types of neoplasia. Because of frequent use and eventual discharge, they have been …

The fish embryo test (FET): origin, applications, and future

T Braunbeck, B Kais, E Lammer, J Otte… - … Science and Pollution …, 2015 - Springer
Originally designed as an alternative for the acute fish toxicity test according to, eg, OECD
TG 203, the fish embryo test (FET) with the zebrafish (Danio rerio) has been optimized …

Selection of priority emerging contaminants in surface waters of India, Pakistan, Bangladesh, and Sri Lanka

M Shafi, R Jan, KM Gani - Chemosphere, 2023 - Elsevier
The challenge of emerging contaminants (ECs) in global surface water bodies and
particularly in low-and middle-income countries such as India, Pakistan, Bangladesh, and …