Salvia miltiorrhiza: a potential red light to the development of cardiovascular diseases

L Wang, R Ma, C Liu, H Liu, R Zhu… - Current …, 2017 - ingentaconnect.com
Salvia miltiorrhiza Bunge, also known as Danshen in Chinese, has been widely used to treat
cardiovascular diseases (CVD) in China and other Asia countries. Here, we summarize …

Role of homocysteine in the ischemic stroke and development of ischemic tolerance

J Lehotský, B Tothová, M Kovalská, D Dobrota… - Frontiers in …, 2016 - frontiersin.org
Homocysteine (Hcy) is a toxic, sulfur-containing intermediate of methionine metabolism.
Hyperhomocysteinemia (hHcy), as a consequence of impaired Hcy metabolism or defects in …

[HTML][HTML] Baicalein administered in the subacute phase ameliorates ischemia-reperfusion-induced brain injury by reducing neuroinflammation and neuronal damage

S Yang, H Wang, Y Yang, R Wang, Y Wang… - Biomedicine & …, 2019 - Elsevier
Ischemic stroke is a cerebrovascular disease with high morbidity, high mortality, and high
disability, representing a serious threat to human life and health. Clinically, the extensive …

Artemisinin attenuated ischemic stroke induced cell apoptosis through activation of ERK1/2/CREB/BCL-2 signaling pathway in vitro and in vivo

T Peng, S Li, L Liu, C Yang, M Farhan… - International …, 2022 - pmc.ncbi.nlm.nih.gov
Ischemic stroke is characterized by the presence of both brain ischemic and reperfusion-
induced injuries in the brain, leading to neuronal dysfunction and death. Artemisinin, an FDA …

A comprehensive and system review for the pharmacological mechanism of action of rhein, an active anthraquinone ingredient

H Sun, G Luo, D Chen, Z **ang - Frontiers in pharmacology, 2016 - frontiersin.org
Rhein is a major medicinal ingredient isolated from several traditional Chinese medicines,
including Rheum palmatum L., Aloe barbadensis Miller, Cassia angustifolia Vahl., and …

The PI3K/AKT pathway—The potential key mechanisms of traditional Chinese medicine for stroke

C Gu, Q Zhang, Y Li, R Li, J Feng, W Chen… - Frontiers in …, 2022 - frontiersin.org
Stroke is associated with a high disability and fatality rate, and adversely affects the quality
of life of patients and their families. Traditional Chinese Medicine (TCM) has been used …

Current evidence of synaptic dysfunction after stroke: Cellular and molecular mechanisms

C Li, M Jiang, ZT Fang, Z Chen, L Li… - CNS Neuroscience …, 2024 - Wiley Online Library
Background Stroke is an acute cerebrovascular disease in which brain tissue is damaged
due to sudden obstruction of blood flow to the brain or the rupture of blood vessels in the …

Anti-apoptosis effect of traditional Chinese medicine in the treatment of cerebral ischemia–reperfusion injury

N Zhao, Y Gao, H Jia, X Jiang - Apoptosis, 2023 - Springer
Cerebral ischemia, one of the leading causes of neurological dysfunction of brain cells,
muscle dysfunction, and death, brings great harm and challenges to individual health …

Proteomics-guided study on buyang huanwu decoction for its neuroprotective and neurogenic mechanisms for transient ischemic stroke: involvements of EGFR/PI3K …

X Chen, H Chen, Y He, S Fu, H Liu, Q Wang… - Molecular …, 2020 - Springer
Abstract Buyang Huanwu Decoction (BHD), a classic traditional Chinese medicine (TCM)
formula, has been used for recovering neurological dysfunctions and treating post-stroke …

Microglial priming of antigen presentation and adaptive stimulation in Alzheimer's disease

R Das, S Chinnathambi - Cellular and Molecular Life Sciences, 2019 - Springer
The prominent pathological consequences of Alzheimer's disease (AD) are the misfolding
and mis-sorting of two cellular proteins, amyloid-β and microtubule-associated protein Tau …