Endosomes are dynamic intracellular compartments that control the sorting of a constant
stream of different transmembrane cargos either for ESCRT‐mediated degradation or for …

The tubular endolysosomal network is a quality control system that ensures the proper
delivery of internalized receptors to specific subcellular destinations in order to maintain …

The Commander complex is required for endosomal recycling of diverse transmembrane
cargos and is mutated in Ritscher-Schinzel syndrome. It comprises two sub-assemblies …

The recycling of membrane proteins from endosomes to the cell surface is vital for cell
signaling and survival. Retriever, a trimeric complex of vacuolar protein-sorting-associated …

The retromer complex has a well-established role in endosomal protein sorting, being
necessary for maintaining the dynamic localisation of hundreds of membrane proteins that …

Endocytic recycling of internalized transmembrane proteins is essential for many important
physiological processes. Recent studies have revealed that retromer-related Sorting Nexin …

The highly conserved retromer complex controls the fate of hundreds of receptors that pass
through the endolysosomal system and is a central regulatory node for diverse metabolic …

Legionella pneumophila promotes its survival and replication in phagocytes by actively
modulating cellular processes using effectors injected into host cells by its Dot/Icm type IV …

To prevail in the interaction with eukaryotic hosts, many bacterial pathogens use protein
secretion systems to release virulence factors at the host–pathogen interface and/or deliver …

Abstract GDP-mannose (GDP-Man) is a key metabolite essential for protein glycosylation
and glycophosphatidylinositol anchor synthesis, and aberrant cellular GDP-Man levels have …