Cancers make their own luck: theories of cancer origins
Cancer has been a leading cause of death for decades. This dismal statistic has increased
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …
Non-small-cell lung cancer
Non-small-cell lung cancer (NSCLC) is one of the most frequent cancer types and is
responsible for the majority of cancer-related deaths worldwide. The management of …
responsible for the majority of cancer-related deaths worldwide. The management of …
IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with high resistance to
therapies. Inflammatory and immunomodulatory signals co-exist in the pancreatic tumour …
therapies. Inflammatory and immunomodulatory signals co-exist in the pancreatic tumour …
[HTML][HTML] Toxicity of airborne nanoparticles: Facts and challenges
Air pollution is one of the most severe environmental health hazards, and airborne
nanoparticles (diameter< 100 nm) are considered particularly hazardous to human health …
nanoparticles (diameter< 100 nm) are considered particularly hazardous to human health …
Dissecting metastasis using preclinical models and methods
Metastasis has long been understood to lead to the overwhelming majority of cancer-related
deaths. However, our understanding of the metastatic process, and thus our ability to …
deaths. However, our understanding of the metastatic process, and thus our ability to …
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
F Bray, M Laversanne, H Sung, J Ferlay… - CA: a cancer journal …, 2024 - Wiley Online Library
This article presents global cancer statistics by world region for the year 2022 based on
updated estimates from the International Agency for Research on Cancer (IARC). There …
updated estimates from the International Agency for Research on Cancer (IARC). There …
[HTML][HTML] IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy
Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …
for the structure and function of IgG. IgG glycome is relatively stable in the state of …
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel
Cancer has long been viewed as a genetic disease of cumulative mutations. This notion is
fuelled by studies showing that ageing tissues are often riddled with clones of complex …
fuelled by studies showing that ageing tissues are often riddled with clones of complex …
Global variations in lung cancer incidence by histological subtype in 2020: a population-based study
Background Lung cancer is the second most common cancer worldwide, yet the distribution
by histological subtype remains unknown. We aimed to quantify the global, regional, and …
by histological subtype remains unknown. We aimed to quantify the global, regional, and …
Tumor macrophage functional heterogeneity can inform the development of novel cancer therapies
I Nasir, C McGuinness, AR Poh, M Ernst, PK Darcy… - Trends in …, 2023 - cell.com
Macrophages represent a key component of the tumor microenvironment (TME) and are
largely associated with poor prognosis. Therapeutic targeting of macrophages has …
largely associated with poor prognosis. Therapeutic targeting of macrophages has …