Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Pseudomonas aeruginosa is associated with several human infections, mainly related to
healthcare services. In the hospital, it is associated with resistance to several antibiotics …

Bacteria and archaea rely on appendages called type IV pili (T4P) to participate in diverse
behaviors including surface sensing, biofilm formation, virulence, protein secretion and …

Type IV pili (T4Ps) are abundant in many bacterial and archaeal species, where they play
important roles in both surface sensing and twitching motility, with implications for adhesion …

Skin and wound infections are serious medical problems, and the diversity of bacteria
makes such infections difficult to treat. Bacteria possess many virulence factors, among …

Archaea use a molecular machine, called the archaellum, to swim. The archaellum consists
of an ATP-powered intracellular motor that drives the rotation of an extracellular filament …

Prophages can alter their bacterial hosts to prevent other phages from infecting the same
cell, a mechanism known as superinfection exclusion (SIE). Such alterations are facilitated …

Clostridioides difficile is a Gram-positive bacillus, which is a frequent cause of
gastrointestinal infections triggered by the depletion of the gut microbiome. Because of the …

Amongst the major types of archaeal filaments, several have been shown to closely
resemble bacterial homologues of the Type IV pili (T4P). Within Sulfolobales, member …

SUMMARY Type IV pili (T4P) are retractable multifunctional nanofibers present on the
surface of numerous bacterial and archaeal species. Their importance to microbiology is …