Laser ablation–inductively coupled plasma–mass spectrometry imaging in biology

PA Doble, RG de Vega, DP Bishop, DJ Hare… - Chemical …, 2021 - ACS Publications
Elemental imaging gives insight into the fundamental chemical makeup of living organisms.
Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements …

Bioimaging mass spectrometry of trace elements–recent advance and applications of LA-ICP-MS: a review

JS Becker, A Matusch, B Wu - Analytica chimica acta, 2014 - Elsevier
Bioimaging using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)
offers the capability to quantify trace elements and isotopes within tissue sections with a …

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

C Giesen, HAO Wang, D Schapiro, N Zivanovic… - Nature …, 2014 - nature.com
Mass cytometry enables high-dimensional, single-cell analysis of cell type and state. In
mass cytometry, rare earth metals are used as reporters on antibodies. Analysis of metal …

Review of the applications of laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) to the analysis of biological samples

D Pozebon, GL Scheffler, VL Dressler… - Journal of Analytical …, 2014 - pubs.rsc.org
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has received
significant attention over the last 10 years and has been widely used for the analysis of …

Lipid imaging by mass spectrometry–a review

D Gode, DA Volmer - Analyst, 2013 - pubs.rsc.org
Mass spectrometry imaging (MSI) has proven to be extremely useful for applications such as
the spatial analysis of peptides and proteins in biological tissue, the performance …

MntABC and MntH contribute to systemic Staphylococcus aureus infection by competing with calprotectin for nutrient manganese

TE Kehl-Fie, Y Zhang, JL Moore, AJ Farrand… - Infection and …, 2013 - Am Soc Microbiol
During infection, vertebrates limit access to manganese and zinc, starving invading
pathogens, such as Staphylococcus aureus, of these essential metals in a process termed …

Single-cell mass spectrometry imaging of multiple drugs and nanomaterials at organelle level

Y Meng, C Gao, Q Lu, S Ma, W Hang - Acs Nano, 2021 - ACS Publications
Mass spectrometry imaging (MSI) techniques make possible the spatial chemical
identification of analytes, especially for biological samples. As a universal energy source …

Quantification strategies for elemental imaging of biological samples using laser ablation-inductively coupled plasma-mass spectrometry

D Hare, C Austin, P Doble - Analyst, 2012 - pubs.rsc.org
This review provides analysts with critical insights of current approaches for quantification by
laser ablation-inductively coupled plasma-mass spectrometry in the field of elemental …

Diagnosis of nephrogenic systemic fibrosis by means of elemental bioimaging and speciation analysis

M Birka, KS Wentker, E Lusmöller… - Analytical …, 2015 - ACS Publications
The combined use of elemental bioimaging and speciation analysis is presented as a novel
means for the diagnosis of nephrogenic systemic fibrosis (NSF), a rare disease occurring …

Elemental bioimaging in kidney by LA–ICP–MS as a tool to study nephrotoxicity and renal protective strategies in cisplatin therapies

E Moreno-Gordaliza, C Giesen, A Lázaro… - Analytical …, 2011 - ACS Publications
A laser ablation inductively coupled plasma mass spectrometry (LA–ICP–MS)-based
methodology is presented for Pt, Cu, and Zn bioimaging on whole kidney 3 μm sagittal …