[HTML][HTML] Molecular mechanisms of stress granule assembly and disassembly
Stress granules (SGs) are membrane-less ribonucleoprotein (RNP)-based cellular
compartments that form in the cytoplasm of a cell upon exposure to various environmental …
compartments that form in the cytoplasm of a cell upon exposure to various environmental …
Stress granules and processing bodies in translational control
P Ivanov, N Kedersha… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Stress granules (SGs) and processing bodies (PBs) are non-membrane-enclosed RNA
granules that dynamically sequester translationally inactive messenger ribonucleoprotein …
granules that dynamically sequester translationally inactive messenger ribonucleoprotein …
Mechanistic insights into mammalian stress granule dynamics
The accumulation of stalled translation preinitiation complexes (PICs) mediates the
condensation of stress granules (SGs). Interactions between prion-related domains and …
condensation of stress granules (SGs). Interactions between prion-related domains and …
[HTML][HTML] Modulation of RNA condensation by the DEAD-box protein eIF4A
Stress granules are condensates of non-translating mRNAs and proteins involved in the
stress response and neurodegenerative diseases. Stress granules form in part through …
stress response and neurodegenerative diseases. Stress granules form in part through …
Mechanisms and regulation of RNA condensation in RNP granule formation
Ribonucleoprotein (RNP) granules are RNA–protein assemblies that are involved in
multiple aspects of RNA metabolism and are linked to memory, development, and disease …
multiple aspects of RNA metabolism and are linked to memory, development, and disease …
From unwinding to clam**—the DEAD box RNA helicase family
RNA helicases of the DEAD box family are present in all eukaryotic cells and in many
bacteria and Archaea. These highly conserved enzymes are required for RNA metabolism …
bacteria and Archaea. These highly conserved enzymes are required for RNA metabolism …
Stress granules, P-bodies and cancer
Cancer cells are exposed to adverse conditions in the tumor microenvironment, and utilize
post-transcriptional control mechanisms to re-program gene expression in ways that …
post-transcriptional control mechanisms to re-program gene expression in ways that …
Decoding human cytomegalovirus
The human cytomegalovirus (HCMV) genome was sequenced 20 years ago. However, like
those of other complex viruses, our understanding of its protein coding potential is far from …
those of other complex viruses, our understanding of its protein coding potential is far from …
[HTML][HTML] Regulation of translation initiation in eukaryotes: mechanisms and biological targets
N Sonenberg, AG Hinnebusch - Cell, 2009 - cell.com
Translational control in eukaryotic cells is critical for gene regulation during nutrient
deprivation and stress, development and differentiation, nervous system function, aging, and …
deprivation and stress, development and differentiation, nervous system function, aging, and …
Targeting the eIF4F translation initiation complex: a critical nexus for cancer development
Elevated protein synthesis is an important feature of many cancer cells and often arises as a
consequence of increased signaling flux channeled to eukaryotic initiation factor 4F (eIF4F) …
consequence of increased signaling flux channeled to eukaryotic initiation factor 4F (eIF4F) …