Swallowing is a complex motor event that is difficult to investigate in man by
neurophysiological experiments. For this reason, the characteristics of the brain stem …

We define these as the motivations and feelings that are associated with changes in the
body's physiological condition and with the autonomic responses and behaviors that occur …

Background & Aims: Irritable bowel syndrome (IBS) is characterized by visceral
hypersensitivity, possibly related to abnormal brain-gut communication. Positron emission …

Using functional magnetic resonance imaging (fMRI), we observed that noxious thermal
stimuli (46° C) produce significant signal change in putative reward circuitry as well as in …

Although the cerebral cortex has been implicated in the control of swallowing, the functional
organization of the human cortical swallowing representation has not been fully …

The purpose of this study was to compare cerebral cortical representation of experimentally
induced reflexive swallow with that of volitional swallow. Eight asymptomatic adults (24–27 …

BACKGROUND & AIMS:: Women have a higher prevalence of irritable bowel syndrome
(IBS) and possible differences in response to treatment, suggesting sex-related differences …

Heartburn is a symptom complex that has traditionally been accepted as an acid-mediated
event and a reliable indicator of gastroesophageal reflux disease. Recently, however, these …

Functional heartburn is a common disorder and appears to be composed of several distinct
subgroups. Identifying the different subgroups based on clinical history only is not …

Progresses in the understanding of human brain‐gut interactions in health and disease
have been limited by the lack of non‐invasive techniques to study brain activity. The advent …