Reactant solubility, which dictates achievable concentrations, and the stability of reaction
intermediates (excited states), solvents modulate the potential energy landscape and …

In terms of fused heterocyclic compounds, pyrrolopyrimidines, and their substituted analogs
are among the most extensively explored scaffolds. Based on the location of the nitrogen …

Multicomponent reactions play a pivotal role in synthesizing 1H-pyrazole-4-carboxamides,
underscoring its significance in sustainable organic synthesis. These compounds, valued for …

Introduction: Multicomponent reactions (MCRs) and green chemistry are essential criteria for
the development of efficient chemical syntheses for valuable organic compounds. Methods …

In this study, a series of novel pyrazole-based compounds were synthesized starting from
the precursor ethyl 3-(4-amino-1-phenyl-3-((4-sulfamoylphenyl) carbamoyl)-1 H pyrazol-5 …

naphthyridines are synthesized using a four-component, one-pot approach. This method
includes the reaction of aromatic aldehyde, malononitrile, 1, 6-dimethylpyridin-2 (1 H)-one …

Pyrazoles are well-known five-membered heterocyclic compounds and are found in a wide
variety of synthetic and natural compounds. Compounds carrying pyrazole scaffolds exhibit …

Herein, we report a one-pot greener methodology for the synthesis of 3-(1 H-indol-3-yl)-2-
phenyl-1 H-benzo [f] indole-4, 9-dione derivatives by the multicomponent reaction of …

In this research various pyridazino [1, 2‐a] indazole and 1H‐indazolo [1, 2‐b] phthalazine
and 1H‐indazolo [1, 2‐b] phthalazine derivatives were produced with a high yield via a multi …