The pharmaceutical industry has found new applications for the use of continuous
processing for the manufacture of new therapies currently in development. The …

Hot-melt extrusion (HME) is a globally recognized, robust, effective technology that
enhances the bioavailability of poorly soluble active pharmaceutical ingredients and offers …

Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …

Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …

As competition in the biopharmaceutical market gets keener due to the market entry of
biosimilars, process analytical technologies (PATs) play an important role for process …

Additive manufacturing (AM) or 3D printing is enabling new directions in product design. The
adoption of AM in various industrial sectors has led to major transformations. Similarly, AM …

In the last decade significant advances have been made in process analytical technologies
and digital manufacturing of pharmaceutical oral solid dosage forms leading to enhanced …

Blending a mixture of powders to a homogeneous system is a crucial step in many
manufacturing processes. To achieve a high quality of the end product, powder mixtures …

A vertical in-line continuous powder mixing device (CMT–Continuous Mixing Technology)
has been modelled with the discrete element method (DEM) utilizing a calibrated cohesive …

The implementation of continuous pharmaceutical manufacturing requires advanced control
strategies rather than traditional end product testing or an operation within a small range of …