Emerging affinity-based proteomic technologies for large-scale plasma profiling in cardiovascular disease

JG Smith, RE Gerszten - Circulation, 2017 - Am Heart Assoc
Plasma biomarkers that reflect molecular states of the cardiovascular system are central for
clinical decision making. Routinely used plasma biomarkers include troponins, natriuretic …

Proteomics, networks and connectivity indices

H González‐Díaz, Y González‐Díaz, L Santana… - …, 2008 - Wiley Online Library
Describing the connectivity of chemical and/or biological systems using networks is a
straight gate for the introduction of mathematical tools in proteomics. Networks, in some …

Plasma Proteome Database as a resource for proteomics research: 2014 update

V Nanjappa, JK Thomas, A Marimuthu… - Nucleic acids …, 2014 - academic.oup.com
Abstract Plasma Proteome Database (PPD; http://www. plasmaproteomedatabase. org/) was
initially described in the year 2005 as a part of Human Proteome Organization's (HUPO's) …

The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins

J Adachi, C Kumar, Y Zhang, JV Olsen, M Mann - Genome biology, 2006 - Springer
Background Urine is a desirable material for the diagnosis and classification of diseases
because of the convenience of its collection in large amounts; however, all of the urinary …

Aptamer-based proteomic profiling reveals novel candidate biomarkers and pathways in cardiovascular disease

D Ngo, S Sinha, D Shen, EW Kuhn, MJ Keyes, X Shi… - Circulation, 2016 - Am Heart Assoc
Background: Single-stranded DNA aptamers are oligonucleotides of≈ 50 base pairs in
length selected for their ability to bind proteins with high specificity and affinity. Emerging …

Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core …

GS Omenn, DJ States, M Adamski, TW Blackwell… - …, 2005 - Wiley Online Library
HUPO initiated the Plasma Proteome Project (PPP) in 2002. Its pilot phase has (1) evaluated
advantages and limitations of many depletion, fractionation, and MS technology …

Plasma Proteome Database as a resource for proteomics research

B Muthusamy, G Hanumanthu, S Suresh, B Rekha… - …, 2005 - Wiley Online Library
Plasma is one of the best studied compartments in the human body and serves as an ideal
body fluid for the diagnosis of diseases. This report provides a detailed functional annotation …

[HTML][HTML] Comprehensive and quantitative proteomic analyses of zebrafish plasma reveals conserved protein profiles between genders and between zebrafish and …

C Li, XF Tan, TK Lim, Q Lin, Z Gong - Scientific reports, 2016 - nature.com
Omic approaches have been increasingly used in the zebrafish model for holistic
understanding of molecular events and mechanisms of tissue functions. However, plasma is …

Cardiovascular proteomics: tools to develop novel biomarkers and potential applications

S Arab, AO Gramolini, P **, T Kislinger… - Journal of the American …, 2006 - jacc.org
Proteomics is the new systems biological approach to the study of proteins and protein
variation on a large scale as a result of biological processes and perturbations. The field is …

Reflections on the HUPO human proteome project, the flagship project of the human proteome organization, at 10 years

GS Omenn - Molecular & Cellular Proteomics, 2021 - ASBMB
We celebrate the 10th anniversary of the launch of the HUPO Human Proteome Project
(HPP) and its major milestone of confident detection of at least one protein from each of 90 …