[HTML][HTML] Inflammation and cardiovascular disease: From mechanisms to therapeutics

A Alfaddagh, SS Martin, TM Leucker, ED Michos… - American journal of …, 2020 - Elsevier
Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …

Inflammaging and oxidative stress in human diseases: from molecular mechanisms to novel treatments

L Zuo, ER Prather, M Stetskiv, DE Garrison… - International journal of …, 2019 - mdpi.com
It has been proposed that a chronic state of inflammation correlated with aging known as
inflammaging, is implicated in multiple disease states commonly observed in the elderly …

Neutrophils: New insights and open questions

K Ley, HM Hoffman, P Kubes, MA Cassatella… - Science …, 2018 - science.org
Neutrophils are the first line of defense against bacteria and fungi and help combat parasites
and viruses. They are necessary for mammalian life, and their failure to recover after …

Myeloperoxidase–A bridge linking inflammation and oxidative stress with cardiovascular disease

G Ndrepepa - Clinica chimica acta, 2019 - Elsevier
Myeloperoxidase (MPO) is a member of the superfamily of heme peroxidases that is mainly
expressed in neutrophils and monocytes. MPO-derived reactive species play a key role in …

Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values

K Dhama, SK Latheef, M Dadar, HA Samad… - Frontiers in molecular …, 2019 - frontiersin.org
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Dual-ligand lanthanide metal–organic framework for sensitive ratiometric fluorescence detection of hypochlorous acid

YQ Sun, Y Cheng, XB Yin - Analytical Chemistry, 2021 - ACS Publications
Sensitivity, selectivity, visible detection, and rapid response are the main concerns for an
analytical method. Herein, we reported a metal–organic framework (MOF)-based ratiometric …

Myeloperoxidase as an active disease biomarker: recent biochemical and pathological perspectives

AA Khan, MA Alsahli, AH Rahmani - Medical sciences, 2018 - mdpi.com
Myeloperoxidase (MPO) belongs to the family of heme-containing peroxidases, produced
mostly from polymorphonuclear neutrophils. The active enzyme (150 kDa) is the product of …

Protein biomarkers of cardiovascular disease and mortality in the community

JE Ho, A Lyass, P Courchesne, G Chen… - Journal of the …, 2018 - Am Heart Assoc
Background The discovery of novel and highly predictive biomarkers of cardiovascular
disease (CVD) has the potential to improve risk‐stratification methods and may be …

[HTML][HTML] Biological markers of oxidative stress: applications to cardiovascular research and practice

E Ho, KK Galougahi, CC Liu, R Bhindi, GA Figtree - Redox biology, 2013 - Elsevier
Oxidative stress is a common mediator in pathogenicity of established cardiovascular risk
factors. Furthermore, it likely mediates effects of emerging, less well-defined variables that …

[HTML][HTML] Novel biomarkers for cardiovascular risk prediction

J Wang, GJ Tan, LN Han, YY Bai, M He… - Journal of geriatric …, 2017 - ncbi.nlm.nih.gov
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. The
primary prevention of CVD is dependent upon the ability to identify high-risk individuals long …