In the recent years, the peroxisome proliferator‐activated receptor‐γ (PPAR‐γ), a well known
target for type II diabetes treatment, has received an increasing attention for its therapeutic …

Hypoxic-ischemic encephalopathy remains a common cause of brain damage in neonates.
Preterm infants have additional complications, as prematurity by itself increases the risk of …

Cannabidiol (CBD) is a non-psychotomimetic phytocannabinoid derived from Cannabis
sativa. It has therapeutic effects in different paradigms of brain injury, acting as a …

Several lines of evidence suggest that peroxisome proliferator-activated receptor-γ (PPAR-γ)
agonists may control brain inflammation and, therefore, may be useful for the treatment of …

Infant rodents emit ultrasonic vocalizations when isolated from dam and littermates. Due to
the context of their occurrence and the well described bidirectional modulation by …

In the present study we examined the long-term effects of neonatal lesion of basal forebrain
cholinergic neurons induced by intracerebroventricular injections of the immunotoxin 192 …

Abstract Hypoxic Ischemic Encephalopathy (HIE) is one of the most deleterious conditions in
the perinatal period and the access to small molecule biomarkers aiding accurate diagnosis …

Progranulin (PGRN) is a secreted protein expressed ubiquitously throughout the body,
including the brain, where it localizes in neurons and is activated microglia. Loss-of-function …

Isoprostanes are prostaglandin-like bioactive molecules generated via nonenzymatic
peroxidation of lipid membrane-derived arachidonic acid by free radicals and reactive …

Background Hypoxic-ischemic encephalopathy (HIE) has deleterious neurological
consequences. To identify patients at risk of neuronal damage deserving implementation of …