The use of herbal medicinal products and supplements has increased tremendously over
the past three decades with not less than 80% of people worldwide relying on them for some …

Aristolochic acids (AAs) are a group of naturally occurring compounds present in many plant
species of the Aristolochiaceae family. Exposure to AA is a significant risk factor for severe …

Chinese herbal medicine has been practiced for the prevention, treatment, and cure of
diseases for thousands of years. Herbal medicine involves the use of natural compounds …

Cancer is the second most common cause of mortality and morbidity in kidney transplant
recipients after cardiovascular disease. Kidney transplant recipients have at least a twofold …

The epithelium lining is defined as the mucosal surfaces of the renal collecting tubules,
calyces and pelvis, as well as the ureter, bladder and urethra. The term “urothelium” is used …

After more than two decades of rising rates, in recent years the total kidney cancer incidence
worldwide has shown signs of stabilizing, or even decreasing. In adults, kidney cancer …

In the early 1900s, numerous seminal publications reported that high rates of cancer
occurred in certain occupations. During this period, work with infectious agents produced …

CONTEXT: The European Association of Urology (EAU) guideline group for upper tract
urothelial carcinoma (UTUC) has prepared updated guidelines to aid clinicians in assessing …

Introduction Herbal products have gained increasing popularity in the last decade, and are
now used by approximately 20% of the population. Herbal products are complex mixtures of …

Aristolochic acid, a potent human carcinogen produced by Aristolochia plants, is associated
with urothelial carcinoma of the upper urinary tract (UUC). Following metabolic activation …