Cutaneous leishmaniasis treatment

P Minodier, P Parola - Travel medicine and infectious disease, 2007 - Elsevier
The causative species of cutaneous leishmaniasis determines the clinical features and
courses, and treatments. Intralesional or systemic antimonials are the gold standard for the …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

Leishmaniasis: prevention, parasite detection and treatment

T Kobets, I Grekov, M Lipoldova - Current Medicinal Chemistry, 2012 - ingentaconnect.com
Leishmaniasis remains a public health problem worldwide, affecting approximately 12
million people in 88 countries; 50 000 die of it each year. The disease is caused by …

Synthesis, leishmanicidal, trypanocidal and cytotoxic activities of quinoline-chalcone and quinoline-chromone hybrids

JC Coa, E García, M Carda, R Agut, ID Vélez… - Medicinal Chemistry …, 2017 - Springer
We report herein the synthesis and biological activities (cytotoxicity, leishmanicidal and
trypanocidal) of six quinoline-chalcone and five quinoline-chromone hybrids. The …

Synthesis, analytical behaviour and biological evaluation of new 4-substituted pyrrolo [1, 2-a] quinoxalines as antileishmanial agents

J Guillon, I Forfar, M Mamani-Matsuda… - Bioorganic & medicinal …, 2007 - Elsevier
An original series of 4-substituted pyrrolo [1, 2-a] quinoxaline derivatives, new structural
analogues of Galipea species quinoline alkaloids, was synthesized from various substituted …

Leishmaniasis: drug resistance and natural products

T Polonio, T Efferth - International journal of molecular …, 2008 - spandidos-publications.com
Epidemics of fatal visceral leishmaniasis caused by the intracellular protozoan Leishmania
are a severe public health problem in tropical and subtropical regions of the world. One …

Nitroaromatic antibiotics as nitrogen oxide sources

AM Rice, Y Long, SB King - Biomolecules, 2021 - mdpi.com
Nitroaromatic antibiotics show activity against anaerobic bacteria and parasites, finding use
in the treatment of Heliobacter pylori infections, tuberculosis, trichomoniasis, human African …

A catalyst-free benzylic C–H bond olefination of azaarenes for direct Mannich-like reactions

Y Yan, K Xu, Y Fang, Z Wang - The Journal of Organic Chemistry, 2011 - ACS Publications
A highly efficient synthesis of trans-alkenylazaarene under catalyst-free conditions was
developed via the addition of methylazaarenes to N-sulfonyl aldimines and a subsequent C …

[HTML][HTML] Structures, targets and recent approaches in anti-leishmanial drug discovery and development

K Seifert - The open medicinal chemistry journal, 2011 - ncbi.nlm.nih.gov
Recent years have seen a significant improvement in available treatment options for
leishmaniasis. Two new drugs, miltefosine and paromomycin, have been registered for the …

Fighting against Leishmaniasis: search of alkaloids as future true potential anti-Leishmanial agents

BB Mishra, RK Singh, A Srivastava… - Mini reviews in …, 2009 - ingentaconnect.com
Leishmaniasis, a group of tropical diseases caused by protozoan parasites of genus
Leishmania, is a major health problem worldwide that affects millions of people especially in …