Chronic active lesions (CAL) are an important manifestation of chronic inflammation in
multiple sclerosis (MS) and have implications for non-relapsing biological progression. In …

Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient
technology has provided enormous gains in sensitivity, resolution, and contrast for …

BACKGROUND AND PURPOSE: Previous studies have suggested that the central vein sign
and iron rims are specific features of MS lesions. Using 3T SWI, we aimed to compare the …

Introduction In multiple sclerosis (MS), paramagnetic rim lesions (PRLs) on MRI identify a
subset of chronic active lesions (CALs), which have been linked through clinical and …

Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …

Background: The central vein sign (CVS) is a radiological feature proposed as a multiple
sclerosis (MS) imaging biomarker able to accurately differentiate MS from other white matter …

Magnetic resonance imaging (MRI) is essential for the early diagnosis of multiple sclerosis
(MS), for investigating the disease pathophysiology, and for discriminating MS from other …

BACKGROUND AND PURPOSE: Radiologically isolated syndrome describes asymptomatic
individuals with incidental radiologic abnormalities suggestive of multiple sclerosis. Recent …

BACKGROUND AND PURPOSE: An early and accurate diagnosis of multiple sclerosis
remains challenging in clinical neurology. Established diagnostic methods have less than …

Although the past decade has seen remarkable progress in the evaluation and management
of multiple sclerosis (MS) and its mimics, many diagnostic, prognostic, and treatment …