Nanoscale strides: exploring innovative therapies for breast cancer treatment

SL Mugundhan, M Mohan - RSC advances, 2024 - pubs.rsc.org
Breast cancer (BC) is a predominant malignancy in women that constitutes approximately
30% of all cancer cases and has a mortality rate of 14% in recent years. The prevailing …

Overall survival and prognostic factors in metastatic triple-negative breast cancer: a national cancer database analysis

M Kesireddy, L Elsayed, VK Shostrom, P Agarwal… - Cancers, 2024 - mdpi.com
Simple Summary Metastatic triple-negative breast cancer is an aggressive cancer with an
average survival of 8 to 13 months. However, survival varies significantly among patients …

FZD7-Targeted Nanoparticles to Enhance Doxorubicin Treatment of Triple-Negative Breast Cancer

EC Hoover, OM Ruggiero, RN Swingler, ES Day - ACS omega, 2024 - ACS Publications
Doxorubicin (DOX) is a chemotherapy agent commonly used to treat triple-negative breast
cancer (TNBC), but it has insufficient efficacy against the disease and considerable toxicity …

[HTML][HTML] Bufotalin suppresses proliferation and metastasis of triple-negative breast cancer cells by promoting apoptosis and inhibiting the STAT3/EMT axis

SJ Park, HJ Jung - Molecules, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is a highly aggressive type of breast cancer and has a
poor prognosis. As standardized TNBC treatment regimens cause drug resistance and …

[HTML][HTML] Therapeutic potential of LINS01 histamine H3 receptor antagonists as antineoplastic agents for triple negative breast cancer

IA Ospital, MAT Delgado, MB Nicoud, MF Corrêa… - Biomedicine & …, 2024 - Elsevier
The aims of this work were to evaluate the expression of histamine H 3 receptor (H 3 R) in
triple negative breast cancer (TNBC) samples and to investigate the antitumoral efficacy and …

[HTML][HTML] Effects of hyaluronan on breast cancer aggressiveness

A Parnigoni, P Moretto, M Viola, E Karousou, A Passi… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is the most common neoplasm in women. Although the
primary tumor does not appear in a vital organ, lethality is due to the ability of tumor cells to …

Phase II clinical trial of pembrolizumab and chemotherapy reveals distinct transcriptomic profiles by radiologic response in metastatic triple-negative breast cancer

AD Wilkerson, PB Parthasarathy… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: A single arm, phase II trial of carboplatin, nab-paclitaxel, and pembrolizumab
(CNP) in metastatic triple-negative breast cancer (mTNBC) was designed to evaluate overall …

[HTML][HTML] Potential application of self-assembled peptides and proteins in breast cancer and cervical cancer

S Zhang, M Chen, Z Geng, T Liu, S Li, Q Yu… - International Journal of …, 2023 - mdpi.com
Ongoing research is gradually broadening the idea of cancer treatment, with attention being
focused on nanoparticles to improve the stability, therapeutic efficacy, targeting, and other …