The gap gene network

J Jaeger - Cellular and Molecular Life Sciences, 2011 - Springer
Gap genes are involved in segment determination during the early development of the fruit
fly Drosophila melanogaster as well as in other insects. This review attempts to synthesize …

The red flour beetle T. castaneum: elaborate genetic toolkit and unbiased large scale RNAi screening to study insect biology and evolution

M Klingler, G Bucher - EvoDevo, 2022 - Springer
The red flour beetle Tribolium castaneum has emerged as an important insect model system
for a variety of topics. With respect to studying gene function, it is second only to the vinegar …

[PDF][PDF] The genome of the model beetle and pest Tribolium castaneum.

S Richards, RA Gibbs, GM Weinstock, SJ Brown… - Nature, 2008 - serval.unil.ch
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful
model organism for the study of generalized insect development, and an important pest of …

The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology

C Schmitt-Engel, D Schultheis, J Schwirz… - Nature …, 2015 - nature.com
Genetic screens are powerful tools to identify the genes required for a given biological
process. However, for technical reasons, comprehensive screens have been restricted to …

Arthropod Segmentation: beyond the Drosophila paradigm

AD Peel, AD Chipman, M Akam - Nature Reviews Genetics, 2005 - nature.com
Most of our knowledge about the mechanisms of segmentation in arthropods comes from
work on Drosophila melanogaster. In recent years it has become clear that this mechanism …

Arthropod segmentation

E Clark, AD Peel, M Akam - Development, 2019 - journals.biologists.com
There is now compelling evidence that many arthropods pattern their segments using a
clock-and-wavefront mechanism, analogous to that operating during vertebrate …

The mysteries of insect RNAi: A focus on dsRNA uptake and transport

AM Vélez, E Fishilevich - Pesticide biochemistry and physiology, 2018 - Elsevier
RNA interference (RNAi) is becoming a practical tool to control insect pests. Many mysteries
of how double-stranded RNA (dsRNA) is transported into, within, and between cells to …

[HTML][HTML] A segmentation gene in tribolium produces a polycistronic mRNA that codes for multiple conserved peptides

J Savard, H Marques-Souza, M Aranda, D Tautz - Cell, 2006 - cell.com
Segmentation genes in insects are required for generating the subdivisions of the early
embryo. We describe here a new member of the gap family of segmentation genes in the …

Temporal control of RNAi reveals both robust and labile feedback loops in the segmentation clock of the red flour beetle

F Kaufholz, J Ulrich, MS Hakeemi, G Bucher - Proceedings of the National …, 2024 - pnas.org
Animals from all major clades have evolved a segmented trunk, reflected in the human spine
or the insect segments. These units emerge during embryogenesis from a posterior segment …

Patterning with clocks and genetic cascades: Segmentation and regionalization of vertebrate versus insect body plans

M Diaz-Cuadros, O Pourquié, E El-Sherif - PLoS Genetics, 2021 - journals.plos.org
Oscillatory and sequential processes have been implicated in the spatial patterning of many
embryonic tissues. For example, molecular clocks delimit segmental boundaries in …