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Wnt signaling in breast cancer: biological mechanisms, challenges and opportunities
X Xu, M Zhang, F Xu, S Jiang - Molecular cancer, 2020 - Springer
Wnt signaling is a highly conserved signaling pathway that plays a critical role in controlling
embryonic and organ development, as well as cancer progression. Genome-wide …
embryonic and organ development, as well as cancer progression. Genome-wide …
Molecular classification of breast cancer
JYS Tsang, MT Gary - Advances in anatomic pathology, 2020 - journals.lww.com
Cancer classification aims to provide an accurate diagnosis of the disease and prediction of
tumor behavior to facilitate oncologic decision making. Traditional breast cancer …
tumor behavior to facilitate oncologic decision making. Traditional breast cancer …
Omitting radiotherapy after breast-conserving surgery in luminal A breast cancer
TJ Whelan, S Smith, S Parpia, AW Fyles… - … England Journal of …, 2023 - Mass Medical Soc
Background Adjuvant radiotherapy is prescribed after breast-conserving surgery to reduce
the risk of local recurrence. However, radiotherapy is inconvenient, costly, and associated …
the risk of local recurrence. However, radiotherapy is inconvenient, costly, and associated …
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin
Triple-negative breast cancer (TNBC) is an aggressive subtype associated with early
metastatic recurrence and worse patient outcomes. TNBC tumors express molecular …
metastatic recurrence and worse patient outcomes. TNBC tumors express molecular …
The dual role of tumor necrosis factor-alpha (TNF-α) in breast cancer: molecular insights and therapeutic approaches
Background Breast cancer is the most prevalent cancer among women worldwide and the
fifth cause of death among all cancer patients. Breast cancer development is driven by …
fifth cause of death among all cancer patients. Breast cancer development is driven by …
Regional nodal irradiation in early-stage breast cancer
TJ Whelan, IA Olivotto, WR Parulekar… - … England Journal of …, 2015 - Mass Medical Soc
Background Most women with breast cancer who undergo breast-conserving surgery
receive whole-breast irradiation. We examined whether the addition of regional nodal …
receive whole-breast irradiation. We examined whether the addition of regional nodal …
An overview of triple-negative breast cancer
P Kumar, R Aggarwal - Archives of gynecology and obstetrics, 2016 - Springer
Purpose Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors
comprising various breast cancers simply defined by the absence of estrogen receptor …
comprising various breast cancers simply defined by the absence of estrogen receptor …