Current understanding of biological interactions and processing of dna origami nanostructures: role of machine learning and implications in drug delivery

M Singh, D Sharma, M Garg, A Kumar, A Baliyan… - Biotechnology …, 2022 - Elsevier
DNA origami has emerged as an exciting avenue that provides a versatile two and three-
dimensional DNA-based platform for nanomedicine and drug delivery applications. Their …

Advancing the utility of DNA origami technique through enhanced stability of DNA-origami-based assemblies

S Manuguri, MK Nguyen, J Loo… - Bioconjugate …, 2022 - ACS Publications
Since its discovery in 2006, the DNA origami technique has revolutionized bottom-up
nanofabrication. This technique is simple yet versatile and enables the fabrication of …

A versatile DNA origami-based plasmonic nanoantenna for label-free single-molecule surface-enhanced Raman spectroscopy

K Tapio, A Mostafa, Y Kanehira, A Suma, A Dutta… - ACS …, 2021 - ACS Publications
DNA origami technology allows for the precise nanoscale assembly of chemical entities that
give rise to sophisticated functional materials. We have created a versatile DNA origami …

Magnetic-responsive surface-enhanced Raman scattering platform with tunable hot spot for ultrasensitive virus nucleic acid detection

B Yin, WKH Ho, Q Zhang, C Li, Y Huang… - … Applied Materials & …, 2022 - ACS Publications
Surface-enhanced Raman scattering (SERS)-based biosensors are promising tools for virus
nucleic acid detection. However, it remains challenging for SERS-based biosensors using a …

Customized scaffolds for direct assembly of functionalized DNA origami

E Oktay, J Bush, M Vargas, DV Scarton… - … Applied Materials & …, 2023 - ACS Publications
Functional DNA origami nanoparticles (DNA-NPs) are used as nanocarriers in a variety of
biomedical applications including targeted drug delivery and vaccine development. DNA …

Cisplatin-cross-linked DNA origami nanostructures for drug delivery applications

L Sala, T Perecko, O Mestek, D Pinkas… - ACS Applied Nano …, 2022 - ACS Publications
Biocompatible DNA origami nanostructures (DONs) attract significant interest as potential
targeted drug carriers. Their sensitivity to various environmental triggers is beneficial as a …

Effect of Ionic Strength on the Thermal Stability of DNA Origami Nanostructures

M Hanke, E Tomm, G Grundmeier, A Keller - ChemBioChem, 2023 - Wiley Online Library
The stability of DNA origami nanostructures in aqueous media is closely tied to the presence
of cations that screen electrostatic inter‐helix repulsion. Here, the thermal melting behavior …

Nucleic acid nanostructures for in vivo applications: The influence of morphology on biological fate

NI Langlois, KY Ma, HA Clark - Applied Physics Reviews, 2023 - pubs.aip.org
The development of programmable biomaterials for use in nanofabrication represents a
major advance for the future of biomedicine and diagnostics. Recent advances in structural …

Lab-on-a-DNA origami: nanoengineered single-molecule platforms

S Kogikoski, J Ameixa, A Mostafa, I Bald - Chemical Communications, 2023 - pubs.rsc.org
DNA origami nanostructures are self-assembled into almost arbitrary two-and three-
dimensional shapes from a long, single-stranded viral scaffold strand and a set of short …

Large-scale formation of DNA origami lattices on silicon

K Tapio, C Kielar, JM Parikka, A Keller… - Chemistry of …, 2023 - ACS Publications
In recent years, hierarchical nanostructures have found applications in fields like
diagnostics, medicine, nano-optics, and nanoelectronics, especially in challenging …