Exosomes: biogenesis, biologic function and clinical potential
Y Zhang, Y Liu, H Liu, WH Tang - Cell & bioscience, 2019 - Springer
Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of
multivesicular bodies and the plasma membrane. They were shown to carry cell-specific …
multivesicular bodies and the plasma membrane. They were shown to carry cell-specific …
Engineering exosomes as refined biological nanoplatforms for drug delivery
Exosomes, a subgroup of extracellular vesicles (EVs), have been recognized as important
mediators of long distance intercellular communication and are involved in a diverse range …
mediators of long distance intercellular communication and are involved in a diverse range …
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …
The impact of storage on extracellular vesicles: A systematic study
S Gelibter, G Marostica, A Mandelli… - Journal of …, 2022 - Wiley Online Library
Mounting evidence suggests that storage has an impact on extracellular vesicles (EVs)
properties. While− 80° C storage is a widespread approach, some authors proposed …
properties. While− 80° C storage is a widespread approach, some authors proposed …
Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …
cargo comprising several populations with unique roles in biological processes. These …
Preservation and storage stability of extracellular vesicles for therapeutic applications
Abstract Recently, extracellular vesicles (EVs)—including exosomes, microvesicles, and
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …
Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies
A Stuendl, M Kunadt, N Kruse, C Bartels, W Moebius… - Brain, 2016 - academic.oup.com
Extracellular α-synuclein has been proposed as a crucial mechanism for induction of
pathological aggregate formation in previously healthy cells. In vitro, extracellular α …
pathological aggregate formation in previously healthy cells. In vitro, extracellular α …
Extracellular vesicles as signaling mediators and disease biomarkers across biological barriers
Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific
biological information and have progressively emerged as key regulators of organized …
biological information and have progressively emerged as key regulators of organized …
Extracellular vesicles in renal disease
D Karpman, A Ståhl, I Arvidsson - Nature Reviews Nephrology, 2017 - nature.com
Extracellular vesicles, such as exosomes and microvesicles, are host cell-derived packages
of information that allow cell–cell communication and enable cells to rid themselves of …
of information that allow cell–cell communication and enable cells to rid themselves of …
Microfluidic‐based exosome analysis for liquid biopsy
B Lin, Y Lei, J Wang, L Zhu, Y Wu, H Zhang… - Small …, 2021 - Wiley Online Library
Liquid biopsy offers non‐invasive and real‐time molecular profiling of individual patients,
and is thus considered a revolutionary technology in precision medicine. Exosomes have …
and is thus considered a revolutionary technology in precision medicine. Exosomes have …