Inductively coupled plasma mass spectrometry (ICP-MS) combines plasma chemistry, which
produces singly charged elemental ions, with mass spectrometric detection. Unlike other …

Elemental imaging gives insight into the fundamental chemical makeup of living organisms.
Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements …

Significance: Essential metals such as copper, iron, manganese, and zinc play a role as
cofactors in the activity of a wide range of processes involved in cellular homeostasis and …

Laser ablation–inductively coupled plasma–mass spectrometry (LA-ICP-MS) is a widely
accepted method for direct sampling of solid materials for trace elemental analysis. The …

Spatial metabolomics can reveal intercellular heterogeneity and tissue organization. Here
we report on the spatial single nuclear metabolomics (SEAM) method, a flexible platform …

Bioimaging using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)
offers the capability to quantify trace elements and isotopes within tissue sections with a …

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) has received
significant attention over the last 10 years and has been widely used for the analysis of …

Iron has a long and storied history in Parkinson disease and related disorders. This
essential micronutrient is critical for normal brain function, but abnormal brain iron …

This review covers developments in the design of Laser Ablation (LA) cells, the associated
transport tubing assembly, and their coupling to Inductively Coupled Plasma-Mass …

Metal biochemistry drives a diverse range of cellular processes associated with
development, health and disease. Determining metal distribution, concentration and flux …