Multivariate data analysis and machine learning in Alzheimer's disease with a focus on structural magnetic resonance imaging

F Falahati, E Westman… - Journal of Alzheimer's …, 2014 - journals.sagepub.com
Machine learning algorithms and multivariate data analysis methods have been widely
utilized in the field of Alzheimer's disease (AD) research in recent years. Advances in …

Commercial volumetric MRI reporting tools in multiple sclerosis: a systematic review of the evidence

Z Mendelsohn, HG Pemberton, J Gray, O Goodkin… - Neuroradiology, 2023 - Springer
Purpose MRI is integral to the diagnosis of multiple sclerosis (MS) and is important for
clinical prognostication. Quantitative volumetric reporting tools (QReports) can improve the …

[HTML][HTML] BIANCA (Brain Intensity AbNormality Classification Algorithm): A new tool for automated segmentation of white matter hyperintensities

L Griffanti, G Zamboni, A Khan, L Li, G Bonifacio… - Neuroimage, 2016 - Elsevier
Reliable quantification of white matter hyperintensities of presumed vascular origin (WMHs)
is increasingly needed, given the presence of these MRI findings in patients with several …

[HTML][HTML] White matter hyperintensity and stroke lesion segmentation and differentiation using convolutional neural networks

R Guerrero, C Qin, O Oktay, C Bowles, L Chen… - NeuroImage: Clinical, 2018 - Elsevier
White matter hyperintensities (WMH) are a feature of sporadic small vessel disease also
frequently observed in magnetic resonance images (MRI) of healthy elderly subjects. The …

[HTML][HTML] Accurate white matter lesion segmentation by k nearest neighbor classification with tissue type priors (kNN-TTPs)

MD Steenwijk, PJW Pouwels, M Daams… - NeuroImage: Clinical, 2013 - Elsevier
Introduction The segmentation and volumetric quantification of white matter (WM) lesions
play an important role in monitoring and studying neurological diseases such as multiple …

[HTML][HTML] Triplanar ensemble U-Net model for white matter hyperintensities segmentation on MR images

V Sundaresan, G Zamboni, PM Rothwell… - Medical image …, 2021 - Elsevier
White matter hyperintensities (WMHs) have been associated with various cerebrovascular
and neurodegenerative diseases. Reliable quantification of WMHs is essential for …

UBO detector–a cluster-based, fully automated pipeline for extracting white matter hyperintensities

J Jiang, T Liu, W Zhu, R Koncz, H Liu, T Lee… - Neuroimage, 2018 - Elsevier
We present 'UBO Detector', a cluster-based, fully automated pipeline for extracting and
calculating variables for regions of white matter hyperintensities (WMH)(available for …

Cross-sectional and longitudinal MRI brain scans reveal accelerated brain aging in multiple sclerosis

EA Høgestøl, T Kaufmann, GO Nygaard… - Frontiers in …, 2019 - frontiersin.org
Multiple sclerosis (MS) is an inflammatory disorder of the central nervous system. By
combining longitudinal MRI-based brain morphometry and brain age estimation using …

Cognitive variability during middle-age: possible association with neurodegeneration and cognitive reserve

D Ferreira, A Machado, Y Molina, A Nieto… - Frontiers in aging …, 2017 - frontiersin.org
Objective: Increased variability in cognition with age has been argued as an indication of
pathological processes. Focusing on early detection of neurodegenerative disorders, we …

Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset

R Heinen, MD Steenwijk, F Barkhof, JM Biesbroek… - Scientific reports, 2019 - nature.com
White matter hyperintensities (WMHs) are a common manifestation of cerebral small vessel
disease, that is increasingly studied with large, pooled multicenter datasets. This data …