Abstract The World Health Organization estimates that 71 million people worldwide have
chronic hepatitis C viral infection. A major challenge is overall lack of public awareness of …

Classical swine fever virus (CSFV) is an ancient pathogen that continues to pose a threat to
animal agriculture worldwide. The virus belongs to the genus Pestivirus and the family …

Modification of the hepatitis C virus (HCV) positive-strand RNA genome by N6-
methyladenosine (m6A) regulates the viral life cycle. This life cycle takes place solely in the …

Abstract Hepatitis E Virus (HEV) genome encodes three proteins including the ORF2 capsid
protein. Recently, we demonstrated that HEV produces three different forms of ORF2:(i) the …

Hepatitis C virus (HCV) is a major worldwide health burden, and a preventive vaccine is
needed for global control or eradication of this virus. A substantial hurdle to an effective HCV …

In this review, we summarize the relevant scientific advances that led to the development of
infectious cell culture systems for hepatitis C virus (HCV) with the corresponding challenges …

Hepatitis C virus (HCV) glycoproteins E1 and E2 form a heterodimer to constitute viral
envelope proteins, which play an essential role in virus entry. E1 does not directly interact …

Hepatitis C virus (HCV) infection has been shown to regulate microRNA 130a (miR-130a) in
patient biopsy specimens and in cultured cells. We sought to identify miR-130a target genes …

The ability to use structure-based design and engineering to control the molecular shape
and reactivity of an immunogen to induce protective responses shows great promise, along …

The overwhelming frequency of metabolic diseases such as obesity and diabetes are
closely related to liver diseases, which might share common pathogenic signaling …