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Role and recent advancements of ionic liquids in drug delivery systems
MK Shukla, H Tiwari, R Verma, WL Dong, S Azizov… - Pharmaceutics, 2023 - mdpi.com
Advancements in the fields of ionic liquids (ILs) broaden its applications not only in
traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids …
traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids …
Protein immobilization on graphene oxide or reduced graphene oxide surface and their applications: Influence over activity, structural and thermal stability of protein
K Chaudhary, K Kumar, P Venkatesu… - Advances in colloid and …, 2021 - Elsevier
Due to the essential role of biological macromolecules in our daily life; it is important to
control the stability and activity of such macromolecules. Therefore, the most promising route …
control the stability and activity of such macromolecules. Therefore, the most promising route …
[HTML][HTML] Alternative excipients for protein stabilization in protein therapeutics: overcoming the limitations of polysorbates
AJ Castañeda Ruiz, MA Shetab Boushehri, T Phan… - Pharmaceutics, 2022 - mdpi.com
Given their safety and efficiency in protecting protein integrity, polysorbates (PSs) have been
the most widely used excipients for the stabilization of protein therapeutics for years. In …
the most widely used excipients for the stabilization of protein therapeutics for years. In …
Expanding the potential role of deep eutectic solvents toward facilitating the structural and thermal stability of α-chymotrypsin
Since the introduction of deep eutectic solvents (DESs), numerous reports have surfaced
describing its tunable properties and environmentally benign nature. Due to such favorable …
describing its tunable properties and environmentally benign nature. Due to such favorable …
Cholinium-based ionic liquids as efficient media for improving the structural and thermal stability of immunoglobulin G antibodies
Among antibody-based biopharmaceuticals, immunoglobulin G (IgG) plays a central role.
However, IgG is a protein and as such easily loses stability, thus compromising its use as an …
However, IgG is a protein and as such easily loses stability, thus compromising its use as an …
Protein aggregation and crystallization with ionic liquids: Insights into the influence of solvent properties
Ionic liquids (ILs) have been used in solvents for proteins in many applications, including
biotechnology, pharmaceutics, and medicine due to their tunable physicochemical and …
biotechnology, pharmaceutics, and medicine due to their tunable physicochemical and …
A Vibrant Accelerating Strategic Solvent System for Sustainability and Functionality for Proteins: Unvarying Structure of Stem Bromelain in Hybrid Ionic Fluids
Very recently, a new class of cosolvents, hybrid ionic fluids (HIFs), have been designed by
combining an ionic liquid (IL) and a deep eutectic solvent (DES) with a common anion. The …
combining an ionic liquid (IL) and a deep eutectic solvent (DES) with a common anion. The …
A good and bad aggregation: Effect of imidazolium-and cholinium-based ionic liquids on the thermal stability of bovine serum albumin
AA Khachatrian, TA Mukhametzyanov… - Journal of Molecular …, 2023 - Elsevier
The present work describes the effect of imidazolium-and cholinium-based ionic liquids (ILs)
on the thermal stability, binding and aggregation of bovine serum albumin (BSA). The …
on the thermal stability, binding and aggregation of bovine serum albumin (BSA). The …
Multicolor, injectable BSA-based lanthanide luminescent hydrogels with biodegradability
YY Pei, JT Wang, L Yuan, Y Luo, XY Niu… - International Journal of …, 2023 - Elsevier
Protein hydrogels have attracted increasing attention because of their excellent
biodegradability and biocompatibility, but frequently suffer from the single structures and …
biodegradability and biocompatibility, but frequently suffer from the single structures and …
Selective Near-Infrared Blood Detection Driven by Ionic Liquid–Dye–Albumin Nanointeractions
DS Darlington, AN Mahurin, K Kapusta, E Suh… - Langmuir, 2023 - ACS Publications
Due to its abundance in blood, a great deal of research has been undertaken to develop
efficient biosensors for serum albumin and provide insight into the interactions that take …
efficient biosensors for serum albumin and provide insight into the interactions that take …