Deciphering breast cancer: from biology to the clinic

E Nolan, GJ Lindeman, JE Visvader - Cell, 2023 - cell.com
Breast cancer remains a leading cause of cancer-related mortality in women, reflecting
profound disease heterogeneity, metastasis, and therapeutic resistance. Over the last …

Triple negative breast cancer: Pitfalls and progress

P Zagami, LA Carey - NPJ breast cancer, 2022 - nature.com
Triple negative breast cancer (TNBC) is characterized by the lack of estrogen and
progesterone receptor expression and lacks HER2 overexpression or gene amplification. It …

Breast cancer, version 3.2024, NCCN clinical practice guidelines in oncology

WJ Gradishar, MS Moran, J Abraham… - Journal of the National …, 2024 - jnccn.org
Breast cancer is treated with a multidisciplinary approach involving surgical oncology,
radiation oncology, and medical oncology. The NCCN Clinical Practice Guidelines in …

Sentinel lymph node biopsy vs no axillary surgery in patients with small breast cancer and negative results on ultrasonography of axillary lymph nodes: the SOUND …

OD Gentilini, E Botteri, C Sangalli, V Galimberti… - JAMA …, 2023 - jamanetwork.com
Importance Sentinel lymph node biopsy (SLNB) is the standard of care for axillary node
staging of patients with early breast cancer (BC), but its necessity can be questioned since …

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

LA Huppert, O Gumusay, D Idossa… - CA: a cancer journal for …, 2023 - Wiley Online Library
Hormone receptor (HR)‐positive and human epidermal growth factor receptor 2 (HER2)‐
negative breast cancer is defined by the presence of the estrogen receptor and/or the …

Biomarkers for adjuvant endocrine and chemotherapy in early-stage breast cancer: ASCO guideline update

F Andre, N Ismaila, KH Allison, WE Barlow… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To update recommendations on appropriate use of breast cancer biomarker
assay results to guide adjuvant endocrine and chemotherapy decisions in early-stage breast …

Axillary surgery in breast cancer—primary results of the INSEMA trial

T Reimer, A Stachs, K Veselinovic… - … England Journal of …, 2024 - Mass Medical Soc
Background Whether surgical axillary staging as part of breast-conserving therapy can be
omitted without compromising survival has remained unclear. Methods In this prospective …

A population-level digital histologic biomarker for enhanced prognosis of invasive breast cancer

M Amgad, JM Hodge, MAT Elsebaie, C Bodelon… - Nature Medicine, 2024 - nature.com
Breast cancer is a heterogeneous disease with variable survival outcomes. Pathologists
grade the microscopic appearance of breast tissue using the Nottingham criteria, which are …

Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

S Loibl, F André, T Bachelot, CH Barrios… - Annals of …, 2024 - annalsofoncology.org
Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
- Annals of Oncology Skip to Main Content Advertisement Annals of Oncology European …

What is known about breast cancer in young women?

JW Zhu, P Charkhchi, S Adekunte, MR Akbari - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is the most common cancer affecting women under 40 years
of age worldwide, with an increasing number of cases diagnosed each year. Despite this …