Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

The science of large-scale brain networks offers a powerful paradigm for investigating
cognitive and affective dysfunction in psychiatric and neurological disorders. This review …

The posterior cingulate cortex is a highly connected and metabolically active brain region.
Recent studies suggest it has an important cognitive role, although there is no consensus …

Though only a decade has elapsed since the default network (DN) was first defined as a
large‐scale brain system, recent years have brought great insight into the network's adaptive …

Resting-state fMRI measures spontaneous low-frequency fluctuations in the BOLD signal to
investigate the functional architecture of the brain. Application of this technique has allowed …

One challenging aspect of the clinical assessment of brain-injured, unresponsive patients is
the lack of an objective measure of consciousness that is independent of the subject's ability …

During resting conditions the brain remains functionally and metabolically active. One
manifestation of this activity that has become an important research tool is spontaneous …

The role of the frontal cortex in consciousness remains a matter of debate. In this
Perspective, we will critically review the clinical and neuroimaging evidence for the …

The concept of consciousness continues to defy definition and elude the grasp of
philosophical and scientific efforts to formulate a testable construct that maps to human …

Consciousness can be defined by two components: arousal (wakefulness) and awareness
(subjective experience). However, neurophysiological consciousness metrics able to …