BACKGROUND: With increasing evidence that hydroperoxides are not only toxic but rather
exert essential physiological functions, also hydroperoxide removing enzymes have to be re …

DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm
function. High levels of oxidative stress result in damage to sperm DNA, RNA transcripts …

Semen analysis is the cornerstone of male fertility evaluation with WHO guidelines providing
the basis for procedural standardization and reference values worldwide. The first WHO …

Oxidative stress plays a major role in the life and death of mammalian spermatozoa. These
gametes are professional generators of reactive oxygen species (ROS), which appear to …

Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

Oxidative stress occurs when the production of potentially destructive reactive oxygen
species (ROS) exceeds the bodies own natural antioxidant defenses, resulting in cellular …

At present infertility is affecting about 15% of couples and male factor is responsible for
almost 50% of infertility cases. Oxidative stress, due to enhanced Reactive Oxygen Species …

One of the major causes of defective sperm function is oxidative stress, which not only
disrupts the integrity of sperm DNA but also limits the fertilizing potential of these cells as a …

Male and female germ lines are vulnerable to oxidative stress. In spermatozoa, such stress
triggers a lipid peroxidation cascade that culminates in the generation of electrophilic lipid …

Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for
male fertility evaluation. While its detrimental implications on sperm function were …