Exploiting unique features of microneedles to modulate immunity

C Edwards, SA Shah, T Gebhardt… - Advanced …, 2023 - Wiley Online Library
Microneedle arrays (MNAs) are small patches containing hundreds of short projections that
deliver signals directly to dermal layers without causing pain. These technologies are of …

Fibronectin-coated metal–phenolic networks for cooperative tumor chemo-/chemodynamic/immune therapy via enhanced ferroptosis-mediated immunogenic cell …

Y Xu, Y Guo, C Zhang, M Zhan, L Jia, S Song, C Jiang… - Acs Nano, 2022 - ACS Publications
The development of nanomedicine formulations to overcome the disadvantages of
traditional chemotherapeutic drugs and integrate cooperative theranostic modes still …

Composite microneedles loaded with Astragalus membranaceus polysaccharide nanoparticles promote wound healing by curbing the ROS/NF-κB pathway to …

X Liu, C Guo, W Yang, W Wang, N Diao, M Cao… - Carbohydrate …, 2024 - Elsevier
The healing of chronic diabetic wounds remains a formidable challenge in modern times. In
this study, a novel traditional Chinese medicine microneedle patch was designed based on …

Polysaccharide-based transdermal drug delivery

J Li, H **ang, Q Zhang, X Miao - Pharmaceuticals, 2022 - mdpi.com
Materials derived from natural plants and animals have great potential for transdermal drug
delivery. Polysaccharides are widely derived from marine, herbal, and microbial sources …

Food polysaccharides: A review on emerging microbial sources, bioactivities, nanoformulations and safety considerations

N Dedhia, SJ Marathe, RS Singhal - Carbohydrate Polymers, 2022 - Elsevier
The ubiquity, low cost and biocompatibility make polysaccharides a material of choice in
food, pharmaceutical, cosmeceutical, textile and paper industries. From the age-old process …

[HTML][HTML] A novel hyaluronic acid-based dissolving microneedle patch loaded with ginsenoside Rg3 liposome for effectively alleviate psoriasis

C Huang, K Gou, X Yue, S Zhao, R Zeng, Y Qu… - Materials & Design, 2022 - Elsevier
Psoriasis is a chronic scaly skin disease, which is associated with abnormal immune system
function, inflammatory cell infiltration. The disadvantages of traditional treatment of psoriasis …

Polymeric microneedles for transdermal drug delivery-a review of recent studies

Z Karim, P Karwa, SRR Hiremath - Journal of Drug Delivery Science and …, 2022 - Elsevier
Transdermal drug delivery is contemplated as one of the top appealing routes for
pharmaceutically active ingredients administration owing to the several benefits, specifically …

Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases

Q Bao, X Zhang, Z Hao, Q Li, F Wu, K Wang, Y Li… - Nano-Micro Letters, 2024 - Springer
The eye, a complex organ isolated from the systemic circulation, presents significant drug
delivery challenges owing to its protective mechanisms, such as the blood-retinal barrier …

Isolation, structural features, and bioactivities of polysaccharides from Panax notoginseng: A review

A Tao, Y Zhang, Z Gan, C Yin, Y Tian, L Zhang… - International Journal of …, 2024 - Elsevier
Panax notoginseng a member of the Araliaceous family, is a traditional Chinese medicinal
and functional food with a long history. This herb contains various compounds, including …