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Genetics, epigenetics and transgenerational transmission of obesity in children
N Panera, C Mandato, A Crudele… - Frontiers in …, 2022 - frontiersin.org
Sedentary lifestyle and consumption of high-calorie foods have caused a relentless increase
of overweight and obesity prevalence at all ages. Its presently epidemic proportion is …
of overweight and obesity prevalence at all ages. Its presently epidemic proportion is …
The genetics of obesity: FTO leads the way
In 2007, an association of single nucleotide polymorphisms (SNPs) in the fat mass and
obesity-associated (FTO) gene region with body mass index (BMI) and risk of obesity was …
obesity-associated (FTO) gene region with body mass index (BMI) and risk of obesity was …
FTO gene polymorphisms and obesity risk: a meta-analysis
Background The pathogenesis of obesity is reportedly related to variations in the fat mass
and an obesity-associated gene (FTO); however, as the number of reports increases …
and an obesity-associated gene (FTO); however, as the number of reports increases …
Gender in childhood obesity: family environment, hormones, and genes
AB Wisniewski, SD Chernausek - Gender medicine, 2009 - Elsevier
Background: The prevalence of obesity among children in the United States represents a
pool of latent morbidity. Though the prevalence of obesity has increased in both boys and …
pool of latent morbidity. Though the prevalence of obesity has increased in both boys and …
The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels
T Berulava, B Horsthemke - European Journal of Human Genetics, 2010 - nature.com
As shown by genome-wide association studies single-nucleotide polymorphisms (SNPs)
within intron 1 of the FTO gene are associated with the body mass index and type II …
within intron 1 of the FTO gene are associated with the body mass index and type II …
[HTML][HTML] Genome wide analysis reveals association of a FTO gene variant with epigenetic changes
Variants of the FTO gene show strong association with obesity, but the mechanisms behind
this association remain unclear. We determined the genome wide DNA methylation profile in …
this association remain unclear. We determined the genome wide DNA methylation profile in …
Increasing heritability of BMI and stronger associations with the FTO gene over childhood
The growing evidence of health risks associated with the rise in childhood obesity adds to
the urgency of understanding the determinants of BMI. Twin analyses on repeated …
the urgency of understanding the determinants of BMI. Twin analyses on repeated …
Polymorphisms of fat mass and obesity-associated gene in the pathogenesis of child and adolescent metabolic syndrome
Y Song, H Wade, B Zhang, W Xu, R Wu, S Li, Q Su - Nutrients, 2023 - mdpi.com
Childhood metabolic syndrome (MetS) is prevalent around the world and is associated with
a high likelihood of suffering from severe diseases such as cardiovascular disease later in …
a high likelihood of suffering from severe diseases such as cardiovascular disease later in …
Genome-wide association study of circulating retinol levels
Retinol is one of the most biologically active forms of vitamin A and is hypothesized to
influence a wide range of human diseases including asthma, cardiovascular disease …
influence a wide range of human diseases including asthma, cardiovascular disease …
FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity
M Hakanen, OT Raitakari, T Lehtimaki… - The Journal of …, 2009 - academic.oup.com
Context: A common variant in the FTO gene, rs9939609, associates with body mass index
(BMI) in adults and in children aged 7 yr or older. Objective: Our aim was to examine the …
(BMI) in adults and in children aged 7 yr or older. Objective: Our aim was to examine the …