Disease manifestations and pathogenic mechanisms of group A Streptococcus

MJ Walker, TC Barnett, JD McArthur… - Clinical microbiology …, 2014 - journals.asm.org
Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …

Streptococcus Adherence and Colonization

AH Nobbs, RJ Lamont… - … and molecular biology …, 2009 - journals.asm.org
Streptococci readily colonize mucosal tissues in the nasopharynx; the respiratory,
gastrointestinal, and genitourinary tracts; and the skin. Each ecological niche presents a …

Streptococcus dysgalactiae subsp. equisimilis infection and its intersection with Streptococcus pyogenes

O **e, MR Davies, SYC Tong - Clinical microbiology reviews, 2024 - journals.asm.org
Streptococcus dysgalactiae subsp. equisimilis (SDSE) is an increasingly recognized cause
of disease in humans. Disease manifestations range from non-invasive superficial skin and …

Molecular insight into invasive group A streptococcal disease

JN Cole, TC Barnett, V Nizet, MJ Walker - Nature Reviews Microbiology, 2011 - nature.com
Streptococcus pyogenes is also known as group A Streptococcus (GAS) and is an important
human pathogen that causes considerable morbidity and mortality worldwide. The GAS …

Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules

BF Cress, JA Englaender, W He… - FEMS microbiology …, 2014 - academic.oup.com
The increasing prevalence of antibiotic-resistant bacteria portends an impending
postantibiotic age, characterized by diminishing efficacy of common antibiotics and routine …

Genome-wide analysis of group A streptococci reveals a mutation that modulates global phenotype and disease specificity

P Sumby, AR Whitney, EA Graviss, FR DeLeo… - PLoS …, 2006 - journals.plos.org
Many human pathogens produce phenotypic variants as a means to circumvent the host
immune system and enhance survival and, as a potential consequence, exhibit increased …

An essential role for phoP in Mycobacterium tuberculosis virulence

E Pérez, S Samper, Y Bordas, C Guilhot… - Molecular …, 2001 - Wiley Online Library
Two‐component regulatory proteins function in bacteria as sensory and adaptive factors in
response to a wide range of environmental stimuli. Some two‐component systems, such as …

Virulence control in group A Streptococcus by a two-component gene regulatory system: Global expression profiling and in vivo infection modeling

MR Graham, LM Smoot, CAL Migliaccio… - Proceedings of the …, 2002 - pnas.org
Two-component gene regulatory systems composed of a membrane-bound sensor and
cytoplasmic response regulator are important mechanisms used by bacteria to sense and …

CovS/CovR of group B streptococcus: a two‐component global regulatory system involved in virulence

MC Lamy, M Zouine, J Fert, M Vergassola… - Molecular …, 2004 - Wiley Online Library
In this study, we carried out a detailed structural and functional analysis of a Streptococcus
agalactiae (GBS) two‐component system which is orthologous to the CovS/CovR …

Virulence factors of Streptococcus anginosus – a molecular perspective

A Kuryłek, M Stasiak, I Kern-Zdanowicz - Frontiers in Microbiology, 2022 - frontiersin.org
Streptococcus anginosus together with S. constellatus and S. intermedius constitute the
Streptococcus anginosus group (SAG), until recently considered to be benign commensals …