Biology of bone tissue: structure, function, and factors that influence bone cells
Bone tissue is continuously remodeled through the concerted actions of bone cells, which
include bone resorption by osteoclasts and bone formation by osteoblasts, whereas …
include bone resorption by osteoclasts and bone formation by osteoblasts, whereas …
Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies
NC Noronha, A Mizukami, C Caliári-Oliveira… - Stem cell research & …, 2019 - Springer
Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …
Osteoblast and osteocyte: games without frontiers
The portrait of osteoblasts and osteocytes has been subjected to a revision, since a large
body of evidence is attributing these cells amazing roles both inside and outside the bone …
body of evidence is attributing these cells amazing roles both inside and outside the bone …
[HTML][HTML] The role of microRNAs in the osteogenic and chondrogenic differentiation of mesenchymal stem cells and bone pathologies
Mesenchymal stem cells (MSCs) have been identified in many adult tissues. MSCs can
regenerate through cell division or differentiate into adipocytes, osteoblasts and …
regenerate through cell division or differentiate into adipocytes, osteoblasts and …
Mesenchymal stem cell migration during bone formation and bone diseases therapy
P Su, Y Tian, C Yang, X Ma, X Wang, J Pei… - International journal of …, 2018 - mdpi.com
During bone modeling, remodeling, and bone fracture repair, mesenchymal stem cells
(MSCs) differentiate into chondrocyte or osteoblast to comply bone formation and …
(MSCs) differentiate into chondrocyte or osteoblast to comply bone formation and …
[HTML][HTML] Co–culture systems of osteoblasts and osteoclasts: Simulating in vitro bone remodeling in regenerative approaches
Bone is an extremely dynamic tissue, undergoing continuous remodeling for its whole
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …
TGF-β family signaling in mesenchymal differentiation
I Grafe, S Alexander, JR Peterson… - Cold Spring …, 2018 - cshperspectives.cshlp.org
Mesenchymal stem cells (MSCs) can differentiate into several lineages during development
and also contribute to tissue homeostasis and regeneration, although the requirements for …
and also contribute to tissue homeostasis and regeneration, although the requirements for …
[HTML][HTML] Current advances in regulation of bone homeostasis
AA Al‐Bari, A Al Mamun - Faseb Bioadvances, 2020 - ncbi.nlm.nih.gov
Bone homeostasis is securely controlled by the dynamic well‐balanced actions among
osteoclasts, osteoblasts and osteocytes. Osteoclasts are large multinucleated cells that …
osteoclasts, osteoblasts and osteocytes. Osteoclasts are large multinucleated cells that …
[HTML][HTML] ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone loss
W Yang, HY Li, YF Wu, RJ Mi, WZ Liu, X Shen… - … Therapy-Nucleic Acids, 2021 - cell.com
N-acetyltransferase 10 (NAT10) is the key enzyme for N4-acetylcytidine (ac4C) modification
of mRNA, which participates in various cellular processes and is related to many diseases …
of mRNA, which participates in various cellular processes and is related to many diseases …
[HTML][HTML] Potential mechanisms underlying the Runx2 induced osteogenesis of bone marrow mesenchymal stem cells
J Xu, Z Li, Y Hou, W Fang - American journal of translational …, 2015 - ncbi.nlm.nih.gov
Bone marrow derived mesenchymal stem cells (BM-MSCs) belong a type of pluripotent stem
cells and can be induced to differentiate into osteoblasts (OB). Runt-related transcription …
cells and can be induced to differentiate into osteoblasts (OB). Runt-related transcription …