This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

Optical imaging of live animals has grown into an important tool in biomedical research as
advances in photonic technology and reporter strategies have led to widespread exploration …

This is a review of recent mathematical and computational advances in optical tomography.
We discuss the physical foundations of forward models for light propagation on microscopic …

There is a wealth of new fluorescent reporter technologies for tagging of many cellular and
subcellular processes in vivo. This imposed contrast is now captured with an increasing …

In vivo imaging of treatment responses at the molecular level could have a significant impact
on the speed of drug discovery and ultimately lead to personalized medicine. Strong interest …

Fluorescence microscopic imaging is widely used in biomedical research to study molecular
and cellular processes in cell culture or tissue samples. This is motivated by the high …

In vivo imaging of molecular events in small animals has great potential to impact basic
science and drug development. For this reason, several imaging technologies have been …

A multichannel spectrally resolved optical tomography system to image molecular targets in
small animals from within a clinical MRI is described. Long source/detector fibers operate in …

Abstract According to World Health Organization estimates, infectious organisms are
responsible for approximately one in four deaths worldwide. Animal models play an …

A hybrid imaging system for simultaneous fluorescence tomography and X-ray computed
tomography (XCT) of small animals has been developed and presented. The system …