Bradykinesia is one of the cardinal motor symptoms of Parkinson's disease and other
parkinsonisms. The various clinical aspects related to bradykinesia and the …

In advanced Parkinson's disease (PD), therapeutic interventions include device-aided
therapies such as continuous subcutaneous apomorphine infusion (CSAI), levodopa …

The neurobiological mechanisms of arousal and anesthesia remain poorly understood.
Recent evidence highlights the key role of interactions between the cerebral cortex and the …

The prevalence of Parkinson's disease (PD) increases with aging and both processes share
similar cellular mechanisms and alterations in the dopaminergic system. Yet it remains to be …

Dopaminergic medication for Parkinson's disease (PD) modulates neuronal oscillations and
functional connectivity (FC) across the basal ganglia-thalamic-cortical circuit. However, the …

The hippocampus (HPC) and medial prefrontal cortex (mPFC) have well-established roles in
cognition, emotion, and sensory processing. In recent years, interests have shifted towards …

In this review, we highlight Professor John Rothwell's contribution towards understanding
basal ganglia function and dysfunction, as well as the effects of subthalamic nucleus deep …

For more than 30 years, deep brain stimulation (DBS) has been used to target the symptoms
of a number of neurological disorders and in particular movement disorders such as …

OBJECTIVE Functional connectivity shows the ability to predict the outcome of subthalamic
nucleus deep brain stimulation (DBS) in Parkinson disease (PD). However, evidence …

This review explores the role of the antisaccadic task in understanding inhibitory
mechanisms in basal ganglia disorders. It conducts a comparative analysis of saccadic …