Comprehensive Overview of Toxoplasma gondii-Induced and Associated Diseases

D Daher, A Shaghlil, E Sobh, M Hamie, ME Hassan… - Pathogens, 2021 - mdpi.com
Toxoplasma gondii (T. gondii) is a prevalent protozoan parasite of medical and veterinary
significance. It is the etiologic agent of toxoplasmosis, a neglected disease in which …

The role of IFN-γ-mediated host immune responses in monitoring and the elimination of Toxoplasma gondii infection

F Ihara, M Yamamoto - International Immunology, 2024 - academic.oup.com
Toxoplasma gondii is a pathogenic protozoan parasite of the Apicomplexa family that affects
approximately 30% of the world's population. Symptoms are usually mild in …

Suicide and inflammation

JJ Donegan, CB Nemeroff - … , Gut-Brain Axis and Immunity in …, 2023 - Springer
Suicide is a leading cause of death worldwide. Although the neurobiological dysfunction
underlying suicidal behavior remains unclear, recent work suggests that the immune system …

Epigenetic Manipulation of Psychiatric Behavioral Disorders Induced by Toxoplasma gondii

K Yin, C Xu, G Zhao, H **e - Frontiers in cellular and infection …, 2022 - frontiersin.org
Toxoplasma gondii is known to have a complex life cycle and infect almost all kinds of warm-
blooded animals around the world. The brain of the host could be persistently infected by …

[HTML][HTML] Chronic infection by atypical Toxoplasma gondii strain induces disturbance in microglia population and altered behaviour in mice

RM de Medeiros Brito, MCM da Silva… - Brain, Behavior, & …, 2023 - Elsevier
Toxoplasma gondii chronic infection is characterized by the establishment of tissue cysts in
the brain and increased levels of IFN-γ, which can lead to brain circuitry interference and …

Fight the fire: Association of cytokine genomic markers and suicidal behavior may pave the way for future therapies

X Gonda, G Serafini, P Dome - Journal of personalized medicine, 2023 - mdpi.com
The fight against suicide is highly challenging as it may be one of the most complex and, at
the same time, most threatening among all psychiatric phenomena. In spite of its huge …

Curcumin ameliorates chronic Toxoplasma gondii infection-induced affective disorders through modulation of proinflammatory cytokines and oxidative stress

F Moradi, N Dashti, A Farahvash… - Iranian Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Objective (s): Long-term infection with Toxoplasma gondii is associated with affective
disorders (ie, anxiety and depression) in adults. We aimed to explore the effects of curcumin …

Chemotherapeutics for Toxoplasma gondii: Molecular Biotargets, Binding Modes, and Structure–Activity Relationship Investigations

RZ Wu, HY Zhou, JF Song, QH **a, W Hu… - Journal of Medicinal …, 2021 - ACS Publications
Toxoplasmosis, an infectious zoonotic disease caused by the apicomplexan parasite
Toxoplasma gondii (T. gondii), is a major worldwide health problem. However, there are …

From the immune system to mood disorders especially induced by Toxoplasma gondii: CD4+ T cell as a bridge

Q Wang, Y Zhong, N Chen, J Chen - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Toxoplasma gondii (T. gondii), a ubiquitous and obligatory intracellular protozoa, not only
alters peripheral immune status, but crosses the blood-brain barrier to trigger brain …

Association of infection with Toxoplasma gondii and Toxocara on cognitive function among US adults aged 60 and over, NHANES 2011–2014

D Kruszon-Moran, D Brody, B Pearce - J Epidemiol Community …, 2023 - jech.bmj.com
Background Toxoplasma gondii and Toxocara are common parasites that infect humans
globally. Our aim was to examine the relationship between T. gondii and Toxocara infection …